A polymer neural probe with tunable flexibility
(2013) 6th International IEEE EMBS Conference on Neural Engineering (NER) p.691-694- Abstract
- A novel polymeric material, off-stoichiometry thiol-ene-epoxy (OSTE+), has been evaluated for the fabrication of neural implants. OSTE+ is easily photo-structurable and exhibits mechanical properties suitable for stable implantation of the probe into brain tissue, while being sufficiently soft at physiological temperatures to reduce living tissue damage. The facile processing of OSTE+ allows use in applications where SU-8 or polyimide currently are the materials of choice. Uniquely, OSTE+ has a Young's modulus of 1.9 GPa at 10 degrees C decreasing almost two orders of magnitude to 30 MPa at 40 degrees C, which can be compared to the Young's modulus of 2.1 GPa for SU-8. We show a probe, with nine gold electrode sites, implanted into 0.5%... (More)
- A novel polymeric material, off-stoichiometry thiol-ene-epoxy (OSTE+), has been evaluated for the fabrication of neural implants. OSTE+ is easily photo-structurable and exhibits mechanical properties suitable for stable implantation of the probe into brain tissue, while being sufficiently soft at physiological temperatures to reduce living tissue damage. The facile processing of OSTE+ allows use in applications where SU-8 or polyimide currently are the materials of choice. Uniquely, OSTE+ has a Young's modulus of 1.9 GPa at 10 degrees C decreasing almost two orders of magnitude to 30 MPa at 40 degrees C, which can be compared to the Young's modulus of 2.1 GPa for SU-8. We show a probe, with nine gold electrode sites, implanted into 0.5% agar at 40 degrees C using active cooling during the implantation. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4367221
- author
- Ejserholm, Fredrik LU ; Vastesson, A. ; Haraldsson, T. ; van der Wijngaart, W. ; Schouenborg, J. ; Wallman, Lars LU and Bengtsson, Martin LU
- organization
- publishing date
- 2013
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- host publication
- 2013 6th International IEEE/Embs Conference on Neural Engineering (NER)
- pages
- 691 - 694
- publisher
- IEEE - Institute of Electrical and Electronics Engineers Inc.
- conference name
- 6th International IEEE EMBS Conference on Neural Engineering (NER)
- conference dates
- 2013-11-06 - 2013-11-08
- external identifiers
-
- wos:000331259200173
- scopus:84897675358
- ISSN
- 1948-3546
- DOI
- 10.1109/NER.2013.6696028
- language
- English
- LU publication?
- yes
- id
- 108242c8-6d97-4026-9909-db7a3f0e2ec1 (old id 4367221)
- date added to LUP
- 2016-04-01 13:22:27
- date last changed
- 2022-01-27 18:52:02
@inproceedings{108242c8-6d97-4026-9909-db7a3f0e2ec1, abstract = {{A novel polymeric material, off-stoichiometry thiol-ene-epoxy (OSTE+), has been evaluated for the fabrication of neural implants. OSTE+ is easily photo-structurable and exhibits mechanical properties suitable for stable implantation of the probe into brain tissue, while being sufficiently soft at physiological temperatures to reduce living tissue damage. The facile processing of OSTE+ allows use in applications where SU-8 or polyimide currently are the materials of choice. Uniquely, OSTE+ has a Young's modulus of 1.9 GPa at 10 degrees C decreasing almost two orders of magnitude to 30 MPa at 40 degrees C, which can be compared to the Young's modulus of 2.1 GPa for SU-8. We show a probe, with nine gold electrode sites, implanted into 0.5% agar at 40 degrees C using active cooling during the implantation.}}, author = {{Ejserholm, Fredrik and Vastesson, A. and Haraldsson, T. and van der Wijngaart, W. and Schouenborg, J. and Wallman, Lars and Bengtsson, Martin}}, booktitle = {{2013 6th International IEEE/Embs Conference on Neural Engineering (NER)}}, issn = {{1948-3546}}, language = {{eng}}, pages = {{691--694}}, publisher = {{IEEE - Institute of Electrical and Electronics Engineers Inc.}}, title = {{A polymer neural probe with tunable flexibility}}, url = {{http://dx.doi.org/10.1109/NER.2013.6696028}}, doi = {{10.1109/NER.2013.6696028}}, year = {{2013}}, }