Are urinary PAHs biomarkers of controlled exposure to diesel exhaust?
(2014) In Biomarkers 19(4). p.332-339- Abstract
- Urinary polycyclic aromatic hydrocarbons (PAHs) were evaluated as possible biomarkers of exposure to diesel exhaust (DE) in two controlled-chamber studies. We report levels of 14 PAHs from 28 subjects in urine that were collected before, immediately after and the morning after exposure. Using linear mixed-effects models, we tested for effects of DE exposure and several covariates (time, age, gender and urinary creatinine) on urinary PAH levels. DE exposures did not significantly alter urinary PAH levels. We conclude that urinary PAHs are not promising biomarkers of short-term exposures to DE in the range of 106-276 mu g/m(3).
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4452268
- author
- Lu, S ; Sobus, J ; Sallsten, G ; Albin, Maria LU ; Pleil, J ; Gudmundsson, Anders LU ; Madden, M ; Strandberg, B ; Wierzbicka, Aneta LU and Rappaport, S
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- diesel exhaust, Biomarker, PAHs, polycyclic aromatic hydrocarbons, urine
- in
- Biomarkers
- volume
- 19
- issue
- 4
- pages
- 332 - 339
- publisher
- Taylor & Francis
- external identifiers
-
- wos:000336730300011
- scopus:84901298187
- pmid:24754404
- ISSN
- 1366-5804
- DOI
- 10.3109/1354750X.2014.910553
- language
- English
- LU publication?
- yes
- id
- 157ffa88-89cd-4016-9560-22982ce1006f (old id 4452268)
- date added to LUP
- 2016-04-01 10:22:32
- date last changed
- 2022-03-19 20:04:15
@article{157ffa88-89cd-4016-9560-22982ce1006f, abstract = {{Urinary polycyclic aromatic hydrocarbons (PAHs) were evaluated as possible biomarkers of exposure to diesel exhaust (DE) in two controlled-chamber studies. We report levels of 14 PAHs from 28 subjects in urine that were collected before, immediately after and the morning after exposure. Using linear mixed-effects models, we tested for effects of DE exposure and several covariates (time, age, gender and urinary creatinine) on urinary PAH levels. DE exposures did not significantly alter urinary PAH levels. We conclude that urinary PAHs are not promising biomarkers of short-term exposures to DE in the range of 106-276 mu g/m(3).}}, author = {{Lu, S and Sobus, J and Sallsten, G and Albin, Maria and Pleil, J and Gudmundsson, Anders and Madden, M and Strandberg, B and Wierzbicka, Aneta and Rappaport, S}}, issn = {{1366-5804}}, keywords = {{diesel exhaust; Biomarker; PAHs; polycyclic aromatic hydrocarbons; urine}}, language = {{eng}}, number = {{4}}, pages = {{332--339}}, publisher = {{Taylor & Francis}}, series = {{Biomarkers}}, title = {{Are urinary PAHs biomarkers of controlled exposure to diesel exhaust?}}, url = {{http://dx.doi.org/10.3109/1354750X.2014.910553}}, doi = {{10.3109/1354750X.2014.910553}}, volume = {{19}}, year = {{2014}}, }