Self-assessed remission rates after electroconvulsive therapy of depressive disorders
(2017) In European Psychiatry 45. p.154-160- Abstract
Background Electroconvulsive therapy (ECT) effectively treats severe depression, but not all patients remit. The aim of the study was to identify clinical factors that associate with ECT-induced remission in a community setting. Methods Depressed patients who underwent ECT in 2011–2014 were identified from the Swedish National Quality Register for ECT. Remission was defined as self-rated Montgomery-Åsberg Depression Rating Scale scores of 0–10 after ECT. Other registers provided data on previous antidepressant use, comorbidities, and demographics. Results Of 1671 patients fulfilling the inclusion criteria, 42.8% achieved remission. Older age, education length over 9 years, psychotic symptoms, shorter duration of preceding antidepressant... (More)
Background Electroconvulsive therapy (ECT) effectively treats severe depression, but not all patients remit. The aim of the study was to identify clinical factors that associate with ECT-induced remission in a community setting. Methods Depressed patients who underwent ECT in 2011–2014 were identified from the Swedish National Quality Register for ECT. Remission was defined as self-rated Montgomery-Åsberg Depression Rating Scale scores of 0–10 after ECT. Other registers provided data on previous antidepressant use, comorbidities, and demographics. Results Of 1671 patients fulfilling the inclusion criteria, 42.8% achieved remission. Older age, education length over 9 years, psychotic symptoms, shorter duration of preceding antidepressant use, pulse width stimulus ≥ 0.50 ms, absence of substance use disorders, anxiety diagnosis, lamotrigine, and benzodiazepines, were associated with remission. Conclusions This study shows that psychotic subtype of depression and older age are clinically relevant predictors of a beneficial ECT effect. Additionally, ECT outcomes can be further improved by optimizing the treatment technique and concomitant medication.
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- author
- Brus, O. ; Cao, Y. ; Gustafsson, E. ; Hultén, Magnus ; Landen, M. ; Lundberg, J. ; Nordanskog, P. LU and Nordenskjöld, Agneta
- organization
- publishing date
- 2017-09-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- ECT, Mania and bipolar disorder, Unipolar depression
- in
- European Psychiatry
- volume
- 45
- pages
- 7 pages
- publisher
- Elsevier Masson SAS
- external identifiers
-
- pmid:28865389
- wos:000414461300021
- scopus:85028504905
- ISSN
- 0924-9338
- DOI
- 10.1016/j.eurpsy.2017.06.015
- language
- English
- LU publication?
- no
- id
- 4516233e-5bcf-4d63-9dab-154686163d69
- date added to LUP
- 2017-10-05 15:23:19
- date last changed
- 2024-09-02 08:25:59
@article{4516233e-5bcf-4d63-9dab-154686163d69, abstract = {{<p>Background Electroconvulsive therapy (ECT) effectively treats severe depression, but not all patients remit. The aim of the study was to identify clinical factors that associate with ECT-induced remission in a community setting. Methods Depressed patients who underwent ECT in 2011–2014 were identified from the Swedish National Quality Register for ECT. Remission was defined as self-rated Montgomery-Åsberg Depression Rating Scale scores of 0–10 after ECT. Other registers provided data on previous antidepressant use, comorbidities, and demographics. Results Of 1671 patients fulfilling the inclusion criteria, 42.8% achieved remission. Older age, education length over 9 years, psychotic symptoms, shorter duration of preceding antidepressant use, pulse width stimulus ≥ 0.50 ms, absence of substance use disorders, anxiety diagnosis, lamotrigine, and benzodiazepines, were associated with remission. Conclusions This study shows that psychotic subtype of depression and older age are clinically relevant predictors of a beneficial ECT effect. Additionally, ECT outcomes can be further improved by optimizing the treatment technique and concomitant medication.</p>}}, author = {{Brus, O. and Cao, Y. and Gustafsson, E. and Hultén, Magnus and Landen, M. and Lundberg, J. and Nordanskog, P. and Nordenskjöld, Agneta}}, issn = {{0924-9338}}, keywords = {{ECT; Mania and bipolar disorder; Unipolar depression}}, language = {{eng}}, month = {{09}}, pages = {{154--160}}, publisher = {{Elsevier Masson SAS}}, series = {{European Psychiatry}}, title = {{Self-assessed remission rates after electroconvulsive therapy of depressive disorders}}, url = {{http://dx.doi.org/10.1016/j.eurpsy.2017.06.015}}, doi = {{10.1016/j.eurpsy.2017.06.015}}, volume = {{45}}, year = {{2017}}, }