High-attenuation artifact reduction in breast tomosynthesis using a novel reconstruction algorithm
(2019) In European Journal of Radiology 116. p.21-26- Abstract
Purpose: To assess the effect on reducing the out-of-plane artifacts from metal objects in breast tomosynthesis (BT)using a novel artifact-reducing reconstruction algorithm in specimen radiography. Methods and Materials: The study was approved by the Regional Ethical Review Board. BT images of 18 partial- and whole mastectomy specimens from women with breast cancer were acquired before and after a needle was inserted close to the lesion. The images were reconstructed using both a standard reconstruction algorithm, and a novel algorithm; the latter uses pre-segmentation to remove highly attenuating artifact-inducing objects from projection images before reconstruction. Images were separately reconstructed with and without segmentation,... (More)
Purpose: To assess the effect on reducing the out-of-plane artifacts from metal objects in breast tomosynthesis (BT)using a novel artifact-reducing reconstruction algorithm in specimen radiography. Methods and Materials: The study was approved by the Regional Ethical Review Board. BT images of 18 partial- and whole mastectomy specimens from women with breast cancer were acquired before and after a needle was inserted close to the lesion. The images were reconstructed using both a standard reconstruction algorithm, and a novel algorithm; the latter uses pre-segmentation to remove highly attenuating artifact-inducing objects from projection images before reconstruction. Images were separately reconstructed with and without segmentation, and combined into an artifact-reduced reconstruction. Standard and artifact-reduced BT-algorithms were compared visually and quantitatively using clinical images of mastectomy specimens and a physical anthropomorphic phantom. Six readers independently assessed the visibility of the lesion with and without artifact-reduction in a side-by-side comparison. A quantitative analysis was performed, comparing the signal-difference to background ratio (SDBR)and artifact spread function (ASF)between the two reconstruction methods. Results: The magnitude of out-of-plane artifacts was clearly reduced with the novel reconstruction compared to BT-images without artifact reduction. Lesion masking by artifacts was largely averted; tumour visibility was comparable to standard BT images without a needle. In 76 ± 8% (standard deviation)of cases overall, readers could confidently state needle location. The same figure was 94 ± 6% for whole mastectomy cases, compared to 62 ± 17% for partial mastectomies. With metal artifact reduction, SDBR increased by 97% in the phantom, and by 69% in the mastectomies. The artifact spread function was substantially narrower. Conclusion: Artifact reduction in BT using a novel reconstruction method enables qualitatively and quantitatively improved clinical use of BT when metal artifacts can be a limiting factor such as in tomosynthesis-guided biopsy.
(Less)
- author
- Dustler, Magnus LU ; Wicklein, Julia ; Förnvik, Hannie LU ; Boita, Joana ; Bakic, Predrag LU and Lång, Kristina LU
- organization
- publishing date
- 2019
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Artifact reduction, Breast imaging, Breast tomosynthesis, Image reconstruction, Mammography
- in
- European Journal of Radiology
- volume
- 116
- pages
- 6 pages
- publisher
- Elsevier
- external identifiers
-
- pmid:31153567
- scopus:85064731563
- ISSN
- 0720-048X
- DOI
- 10.1016/j.ejrad.2019.04.014
- language
- English
- LU publication?
- yes
- id
- 4777e5b7-b389-4323-810c-6d5845afbb4b
- date added to LUP
- 2019-05-02 14:54:34
- date last changed
- 2024-03-03 03:05:04
@article{4777e5b7-b389-4323-810c-6d5845afbb4b,
abstract = {{<p>Purpose: To assess the effect on reducing the out-of-plane artifacts from metal objects in breast tomosynthesis (BT)using a novel artifact-reducing reconstruction algorithm in specimen radiography. Methods and Materials: The study was approved by the Regional Ethical Review Board. BT images of 18 partial- and whole mastectomy specimens from women with breast cancer were acquired before and after a needle was inserted close to the lesion. The images were reconstructed using both a standard reconstruction algorithm, and a novel algorithm; the latter uses pre-segmentation to remove highly attenuating artifact-inducing objects from projection images before reconstruction. Images were separately reconstructed with and without segmentation, and combined into an artifact-reduced reconstruction. Standard and artifact-reduced BT-algorithms were compared visually and quantitatively using clinical images of mastectomy specimens and a physical anthropomorphic phantom. Six readers independently assessed the visibility of the lesion with and without artifact-reduction in a side-by-side comparison. A quantitative analysis was performed, comparing the signal-difference to background ratio (SDBR)and artifact spread function (ASF)between the two reconstruction methods. Results: The magnitude of out-of-plane artifacts was clearly reduced with the novel reconstruction compared to BT-images without artifact reduction. Lesion masking by artifacts was largely averted; tumour visibility was comparable to standard BT images without a needle. In 76 ± 8% (standard deviation)of cases overall, readers could confidently state needle location. The same figure was 94 ± 6% for whole mastectomy cases, compared to 62 ± 17% for partial mastectomies. With metal artifact reduction, SDBR increased by 97% in the phantom, and by 69% in the mastectomies. The artifact spread function was substantially narrower. Conclusion: Artifact reduction in BT using a novel reconstruction method enables qualitatively and quantitatively improved clinical use of BT when metal artifacts can be a limiting factor such as in tomosynthesis-guided biopsy.</p>}},
author = {{Dustler, Magnus and Wicklein, Julia and Förnvik, Hannie and Boita, Joana and Bakic, Predrag and Lång, Kristina}},
issn = {{0720-048X}},
keywords = {{Artifact reduction; Breast imaging; Breast tomosynthesis; Image reconstruction; Mammography}},
language = {{eng}},
pages = {{21--26}},
publisher = {{Elsevier}},
series = {{European Journal of Radiology}},
title = {{High-attenuation artifact reduction in breast tomosynthesis using a novel reconstruction algorithm}},
url = {{http://dx.doi.org/10.1016/j.ejrad.2019.04.014}},
doi = {{10.1016/j.ejrad.2019.04.014}},
volume = {{116}},
year = {{2019}},
}