Four-dimensional in vivo X-ray microscopy with projection-guided gating
(2015) In Scientific Reports 5.- Abstract
Visualizing fast micrometer scale internal movements of small animals is a key challenge for functional anatomy, physiology and biomechanics. We combine phase contrast tomographic microscopy (down to 3.3 μm voxel size) with retrospective, projection-based gating (in the order of hundreds of microseconds) to improve the spatiotemporal resolution by an order of magnitude over previous studies. We demonstrate our method by visualizing 20 three-dimensional snapshots through the 150 Hz oscillations of the blowfly flight motor.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4cf28b13-866a-48aa-8bcc-31ac25b22a65
- author
- Mokso, Rajmund LU ; Schwyn, Daniel A. ; Walker, Simon M. ; Doube, Michael ; Wicklein, Martina ; Müller, Tonya ; Stampanoni, Marco ; Taylor, Graham K. and Krapp, Holger G.
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- in
- Scientific Reports
- volume
- 5
- article number
- 8727
- publisher
- Nature Publishing Group
- external identifiers
-
- scopus:84924869329
- pmid:25762080
- ISSN
- 2045-2322
- DOI
- 10.1038/srep08727
- language
- English
- LU publication?
- no
- id
- 4cf28b13-866a-48aa-8bcc-31ac25b22a65
- date added to LUP
- 2017-09-19 14:38:06
- date last changed
- 2024-09-17 08:10:42
@article{4cf28b13-866a-48aa-8bcc-31ac25b22a65, abstract = {{<p>Visualizing fast micrometer scale internal movements of small animals is a key challenge for functional anatomy, physiology and biomechanics. We combine phase contrast tomographic microscopy (down to 3.3 μm voxel size) with retrospective, projection-based gating (in the order of hundreds of microseconds) to improve the spatiotemporal resolution by an order of magnitude over previous studies. We demonstrate our method by visualizing 20 three-dimensional snapshots through the 150 Hz oscillations of the blowfly flight motor.</p>}}, author = {{Mokso, Rajmund and Schwyn, Daniel A. and Walker, Simon M. and Doube, Michael and Wicklein, Martina and Müller, Tonya and Stampanoni, Marco and Taylor, Graham K. and Krapp, Holger G.}}, issn = {{2045-2322}}, language = {{eng}}, publisher = {{Nature Publishing Group}}, series = {{Scientific Reports}}, title = {{Four-dimensional in vivo X-ray microscopy with projection-guided gating}}, url = {{http://dx.doi.org/10.1038/srep08727}}, doi = {{10.1038/srep08727}}, volume = {{5}}, year = {{2015}}, }