Hepatosplenic candidiasis after neutropenic phase of acute leukaemia
(1999) In Medical Oncology 16(2). p.42-139- Abstract
Hepatosplenic candidiasis following granulocytopenic periods is a relatively recently recognised problem in immunocompromised patients, particularly in those with acute leukaemia. We present three patients in whom diagnosis of hepatosplenic candidiasis was suspected on the basis of ultrasonographic (US), computed tomographic (CT) findings and confirmed by laparoscopy and biopsy of liver lesions. All three patients were successfully treated briefly with amphotericin B, followed by a longer period of fluconazole. In one patient laparotomy and surgical evacuation of abscesses was performed. This condition could be more often recognised by careful follow-up of liver function test, C-reactive protein level, ultrasonography, CT and MRI after... (More)
Hepatosplenic candidiasis following granulocytopenic periods is a relatively recently recognised problem in immunocompromised patients, particularly in those with acute leukaemia. We present three patients in whom diagnosis of hepatosplenic candidiasis was suspected on the basis of ultrasonographic (US), computed tomographic (CT) findings and confirmed by laparoscopy and biopsy of liver lesions. All three patients were successfully treated briefly with amphotericin B, followed by a longer period of fluconazole. In one patient laparotomy and surgical evacuation of abscesses was performed. This condition could be more often recognised by careful follow-up of liver function test, C-reactive protein level, ultrasonography, CT and MRI after recovery from chemotherapy-induced neutropenia.
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- author
- Colović, M ; LAZAREVIC, VLADIMIR LU ; Colović, R ; Janković, G ; Suvajdzić, N ; Bogdanović, A and Bila, J
- publishing date
- 1999-07
- type
- Contribution to journal
- publication status
- published
- keywords
- Adult, Amphotericin B, Antifungal Agents, Antineoplastic Combined Chemotherapy Protocols, Candidiasis, Female, Fluconazole, Humans, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia-Lymphoma, Adult T-Cell, Liver Diseases, Male, Middle Aged, Neutropenia, Opportunistic Infections, Splenic Diseases
- in
- Medical Oncology
- volume
- 16
- issue
- 2
- pages
- 4 pages
- publisher
- Humana Press
- external identifiers
-
- scopus:0032814026
- pmid:10456663
- ISSN
- 1357-0560
- language
- English
- LU publication?
- no
- id
- 4d2560ea-5dc6-4983-a2d1-fcb637669742
- date added to LUP
- 2016-05-24 17:25:54
- date last changed
- 2024-08-18 03:05:42
@article{4d2560ea-5dc6-4983-a2d1-fcb637669742, abstract = {{<p>Hepatosplenic candidiasis following granulocytopenic periods is a relatively recently recognised problem in immunocompromised patients, particularly in those with acute leukaemia. We present three patients in whom diagnosis of hepatosplenic candidiasis was suspected on the basis of ultrasonographic (US), computed tomographic (CT) findings and confirmed by laparoscopy and biopsy of liver lesions. All three patients were successfully treated briefly with amphotericin B, followed by a longer period of fluconazole. In one patient laparotomy and surgical evacuation of abscesses was performed. This condition could be more often recognised by careful follow-up of liver function test, C-reactive protein level, ultrasonography, CT and MRI after recovery from chemotherapy-induced neutropenia.</p>}}, author = {{Colović, M and LAZAREVIC, VLADIMIR and Colović, R and Janković, G and Suvajdzić, N and Bogdanović, A and Bila, J}}, issn = {{1357-0560}}, keywords = {{Adult; Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Candidiasis; Female; Fluconazole; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia-Lymphoma, Adult T-Cell; Liver Diseases; Male; Middle Aged; Neutropenia; Opportunistic Infections; Splenic Diseases}}, language = {{eng}}, number = {{2}}, pages = {{42--139}}, publisher = {{Humana Press}}, series = {{Medical Oncology}}, title = {{Hepatosplenic candidiasis after neutropenic phase of acute leukaemia}}, volume = {{16}}, year = {{1999}}, }