Inflammatory Cytokines and Biomarkers of Cartilage Metabolism 8 Years After Anterior Cruciate Ligament Reconstruction: Results From Operated and Contralateral Knees.
(2015) In The American journal of sports medicine- Abstract
- Patients who sustain an acute anterior cruciate ligament (ACL) rupture are at increased risk to develop posttraumatic arthritis (PTA) in the injured knee whether the ACL is reconstructed or treated nonoperatively. Inflammatory cytokines and cartilage degradation biomarkers are elevated at the time of acute injury and postoperatively. This suggests that one mechanism for PTA may be an inflammatory degradative process initiated on the acute injury and sustained for some length of time independent of whether adequate joint stability is restored.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/5258138
- author
- Åhlén, Martina ; Roshani, Leyla ; Lidén, Mattias ; Struglics, André LU ; Rostgård-Christensen, Lars and Kartus, Jüri
- organization
- publishing date
- 2015-03-18
- type
- Contribution to journal
- publication status
- published
- subject
- in
- The American journal of sports medicine
- publisher
- SAGE Publications
- external identifiers
-
- pmid:25787698
- scopus:84930532671
- pmid:25787698
- ISSN
- 1552-3365
- DOI
- 10.1177/0363546515574059
- language
- English
- LU publication?
- yes
- id
- aa19d62e-9ecd-4c34-abe4-d5dcdf21b048 (old id 5258138)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/25787698?dopt=Abstract
- date added to LUP
- 2016-04-04 09:15:41
- date last changed
- 2022-04-23 19:46:25
@article{aa19d62e-9ecd-4c34-abe4-d5dcdf21b048, abstract = {{Patients who sustain an acute anterior cruciate ligament (ACL) rupture are at increased risk to develop posttraumatic arthritis (PTA) in the injured knee whether the ACL is reconstructed or treated nonoperatively. Inflammatory cytokines and cartilage degradation biomarkers are elevated at the time of acute injury and postoperatively. This suggests that one mechanism for PTA may be an inflammatory degradative process initiated on the acute injury and sustained for some length of time independent of whether adequate joint stability is restored.}}, author = {{Åhlén, Martina and Roshani, Leyla and Lidén, Mattias and Struglics, André and Rostgård-Christensen, Lars and Kartus, Jüri}}, issn = {{1552-3365}}, language = {{eng}}, month = {{03}}, publisher = {{SAGE Publications}}, series = {{The American journal of sports medicine}}, title = {{Inflammatory Cytokines and Biomarkers of Cartilage Metabolism 8 Years After Anterior Cruciate Ligament Reconstruction: Results From Operated and Contralateral Knees.}}, url = {{http://dx.doi.org/10.1177/0363546515574059}}, doi = {{10.1177/0363546515574059}}, year = {{2015}}, }