Prophylactic treatment with S100A9 inhibitor paquinimod reduces pathology in experimental collagenase-induced osteoarthritis.
(2015) In Annals of the Rheumatic Diseases 74(12). p.2254-2258- Abstract
- Alarmins S100A8/A9 regulate pathology in experimental osteoarthritis (OA). Paquinimod is an immunomodulatory compound preventing S100A9 binding to TLR-4. We investigated the effect of paquinimod on experimental OA and human OA synovium.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/5453272
- author
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Annals of the Rheumatic Diseases
- volume
- 74
- issue
- 12
- pages
- 2254 - 2258
- publisher
- BMJ Publishing Group
- external identifiers
-
- pmid:25969431
- wos:000365846400029
- pmid:25969431
- scopus:84945246230
- ISSN
- 1468-2060
- DOI
- 10.1136/annrheumdis-2014-206517
- language
- English
- LU publication?
- yes
- id
- 9a4db149-513a-4f4d-8da3-40c8f85fb27a (old id 5453272)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/25969431?dopt=Abstract
- date added to LUP
- 2016-04-01 10:51:43
- date last changed
- 2022-04-04 21:57:17
@article{9a4db149-513a-4f4d-8da3-40c8f85fb27a, abstract = {{Alarmins S100A8/A9 regulate pathology in experimental osteoarthritis (OA). Paquinimod is an immunomodulatory compound preventing S100A9 binding to TLR-4. We investigated the effect of paquinimod on experimental OA and human OA synovium.}}, author = {{Schelbergen, R F and Geven, E J and van den Bosch, M H J and Eriksson, H and Leanderson, Tomas and Vogl, T and Roth, J and van de Loo, F A J and Koenders, M I and van der Kraan, P M and van den Berg, W B and Blom, A B and van Lent, P L E M}}, issn = {{1468-2060}}, language = {{eng}}, number = {{12}}, pages = {{2254--2258}}, publisher = {{BMJ Publishing Group}}, series = {{Annals of the Rheumatic Diseases}}, title = {{Prophylactic treatment with S100A9 inhibitor paquinimod reduces pathology in experimental collagenase-induced osteoarthritis.}}, url = {{http://dx.doi.org/10.1136/annrheumdis-2014-206517}}, doi = {{10.1136/annrheumdis-2014-206517}}, volume = {{74}}, year = {{2015}}, }