Cutaneous human papillomavirus 88: Remarkable differences in viral load.
(2008) In International Journal of Cancer 122(2). p.477-480- Abstract
- A human papillomavirus (HPV) was cloned from a patient with multiple squamous cell carcinomas (SCCs) and identified as HPV88, recently categorized into a new species within the genus Gamma. The HPV88 viral load in an SCC of the index patient exceeded 1 million copies/cell. By contrast, a survey of 447 skin lesions (79 actinic keratoses, 73 seborrhoeic keratoses, 169 basal cell carcinomas and 126 SCCs) and 362 healthy skin biopsies found detectable HPV88 DNA in only 7 specimens. All these had very low viral loads (<1 copy/10(3) cells) implying extreme biological variability in viral load.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/608603
- author
- Ekström, Johanna LU ; Handisurya, Alessandra ; Forslund, Ola LU ; Geusau, Alexandra ; Kirnbauer, Reinhard and Dillner, Joakim LU
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- published
- subject
- in
- International Journal of Cancer
- volume
- 122
- issue
- 2
- pages
- 477 - 480
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- wos:000251704400031
- scopus:36849054070
- ISSN
- 0020-7136
- DOI
- 10.1002/ijc.23115
- language
- English
- LU publication?
- yes
- id
- 1ac0623c-7ca9-40e3-b4bf-0852c092dad0 (old id 608603)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17935140&dopt=Abstract
- date added to LUP
- 2016-04-01 12:00:39
- date last changed
- 2022-01-26 21:28:32
@article{1ac0623c-7ca9-40e3-b4bf-0852c092dad0, abstract = {{A human papillomavirus (HPV) was cloned from a patient with multiple squamous cell carcinomas (SCCs) and identified as HPV88, recently categorized into a new species within the genus Gamma. The HPV88 viral load in an SCC of the index patient exceeded 1 million copies/cell. By contrast, a survey of 447 skin lesions (79 actinic keratoses, 73 seborrhoeic keratoses, 169 basal cell carcinomas and 126 SCCs) and 362 healthy skin biopsies found detectable HPV88 DNA in only 7 specimens. All these had very low viral loads (<1 copy/10(3) cells) implying extreme biological variability in viral load.}}, author = {{Ekström, Johanna and Handisurya, Alessandra and Forslund, Ola and Geusau, Alexandra and Kirnbauer, Reinhard and Dillner, Joakim}}, issn = {{0020-7136}}, language = {{eng}}, number = {{2}}, pages = {{477--480}}, publisher = {{John Wiley & Sons Inc.}}, series = {{International Journal of Cancer}}, title = {{Cutaneous human papillomavirus 88: Remarkable differences in viral load.}}, url = {{http://dx.doi.org/10.1002/ijc.23115}}, doi = {{10.1002/ijc.23115}}, volume = {{122}}, year = {{2008}}, }