The Mhc class II of the Black grouse (Tetrao tetrix) consists of low numbers of B and Y genes with variable diversity and expression
(2007) In Immunogenetics 59(9). p.725-734- Abstract
- We found that the Black grouse (Tetrao tetrix) possess low numbers of Mhc class II B (BLB) and Y (YLB) genes with variable diversity and expression. We have therefore shown, for the first time, that another bird species (in this case, a wild lek-breeding galliform) shares several features of the simple Mhc of the domestic chicken (Gallus gallus). The Black grouse BLB genes showed the same level of polymorphism that has been reported in chicken, and we also found indications of balancing selection in the peptide-binding regions. The YLB genes were less variable than the BLB genes, also in accordance with earlier studies in chicken, although their functional significance still remains obscure. We hypothesize that the YLB genes could have... (More)
- We found that the Black grouse (Tetrao tetrix) possess low numbers of Mhc class II B (BLB) and Y (YLB) genes with variable diversity and expression. We have therefore shown, for the first time, that another bird species (in this case, a wild lek-breeding galliform) shares several features of the simple Mhc of the domestic chicken (Gallus gallus). The Black grouse BLB genes showed the same level of polymorphism that has been reported in chicken, and we also found indications of balancing selection in the peptide-binding regions. The YLB genes were less variable than the BLB genes, also in accordance with earlier studies in chicken, although their functional significance still remains obscure. We hypothesize that the YLB genes could have been under purifying selection, just as the mammal Mhc-E gene cluster. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/657339
- author
- Strand, Tanja ; Westerdahl, Helena LU ; Hoglund, Jacob ; Alatalo, Rauno V. and Siitari, Heli
- organization
- publishing date
- 2007
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Rfp-Y, BLB, purifying selection, avian Mhc, Mhc class II, YLB
- in
- Immunogenetics
- volume
- 59
- issue
- 9
- pages
- 725 - 734
- publisher
- Springer
- external identifiers
-
- wos:000249503200004
- scopus:34548699489
- ISSN
- 1432-1211
- DOI
- 10.1007/s00251-007-0234-6
- language
- English
- LU publication?
- yes
- id
- a5d05870-270b-4027-8cb3-b505ee003b12 (old id 657339)
- date added to LUP
- 2016-04-01 16:23:48
- date last changed
- 2022-03-30 07:31:20
@article{a5d05870-270b-4027-8cb3-b505ee003b12,
abstract = {{We found that the Black grouse (Tetrao tetrix) possess low numbers of Mhc class II B (BLB) and Y (YLB) genes with variable diversity and expression. We have therefore shown, for the first time, that another bird species (in this case, a wild lek-breeding galliform) shares several features of the simple Mhc of the domestic chicken (Gallus gallus). The Black grouse BLB genes showed the same level of polymorphism that has been reported in chicken, and we also found indications of balancing selection in the peptide-binding regions. The YLB genes were less variable than the BLB genes, also in accordance with earlier studies in chicken, although their functional significance still remains obscure. We hypothesize that the YLB genes could have been under purifying selection, just as the mammal Mhc-E gene cluster.}},
author = {{Strand, Tanja and Westerdahl, Helena and Hoglund, Jacob and Alatalo, Rauno V. and Siitari, Heli}},
issn = {{1432-1211}},
keywords = {{Rfp-Y; BLB; purifying selection; avian Mhc; Mhc class II; YLB}},
language = {{eng}},
number = {{9}},
pages = {{725--734}},
publisher = {{Springer}},
series = {{Immunogenetics}},
title = {{The Mhc class II of the Black grouse (Tetrao tetrix) consists of low numbers of B and Y genes with variable diversity and expression}},
url = {{http://dx.doi.org/10.1007/s00251-007-0234-6}},
doi = {{10.1007/s00251-007-0234-6}},
volume = {{59}},
year = {{2007}},
}