Arynes in the Monoarylation of Unprotected Carbohydrate Amines
(2018) In Organic Letters 20(3). p.616-619- Abstract
A CsF-mediated method has been developed for the N-arylation of amino sugars that affords good to excellent yields of arylated products under mild conditions involving the in situ generation of arynes. The reaction conditions tolerate a variety of common carbohydrate protecting groups and also performs exceptionally well on unprotected amino sugar derivatives. The reactions are scalable in moderate to good yields with broad scope.
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https://lup.lub.lu.se/record/66fb37bb-e697-48a1-9afc-d5ceebfc11c1
- author
- Pal, Kumar Bhaskar ; Mahanti, Mukul LU and Nilsson, Ulf J. LU
- organization
- publishing date
- 2018-02-02
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Organic Letters
- volume
- 20
- issue
- 3
- pages
- 4 pages
- publisher
- The American Chemical Society (ACS)
- external identifiers
-
- pmid:29359567
- scopus:85041603885
- ISSN
- 1523-7060
- DOI
- 10.1021/acs.orglett.7b03741
- language
- English
- LU publication?
- yes
- id
- 66fb37bb-e697-48a1-9afc-d5ceebfc11c1
- date added to LUP
- 2018-02-21 10:03:56
- date last changed
- 2024-09-02 16:03:02
@article{66fb37bb-e697-48a1-9afc-d5ceebfc11c1, abstract = {{<p>A CsF-mediated method has been developed for the N-arylation of amino sugars that affords good to excellent yields of arylated products under mild conditions involving the in situ generation of arynes. The reaction conditions tolerate a variety of common carbohydrate protecting groups and also performs exceptionally well on unprotected amino sugar derivatives. The reactions are scalable in moderate to good yields with broad scope.</p>}}, author = {{Pal, Kumar Bhaskar and Mahanti, Mukul and Nilsson, Ulf J.}}, issn = {{1523-7060}}, language = {{eng}}, month = {{02}}, number = {{3}}, pages = {{616--619}}, publisher = {{The American Chemical Society (ACS)}}, series = {{Organic Letters}}, title = {{Arynes in the Monoarylation of Unprotected Carbohydrate Amines}}, url = {{http://dx.doi.org/10.1021/acs.orglett.7b03741}}, doi = {{10.1021/acs.orglett.7b03741}}, volume = {{20}}, year = {{2018}}, }