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An overview of the transport of liquid molecules through structured polymer films, barriers and composites – Experiments correlated to structure-based simulations

Gårdebjer, Sofie LU ; Larsson, Mikael ; Gebäck, Tobias ; Skepö, Marie LU and Larsson, Anette (2018) In Advances in Colloid and Interface Science 256. p.48-64
Abstract

Films engineered to control the transport of liquids are widely used through society. Examples include barriers in packaging, wound care products, and controlled release coatings in pharmaceutics. When observed at the macroscopic scale such films commonly appear homogeneous, however, a closer look reveals a complex nano- and microstructure that together with the chemical properties of the different domains control the transport properties. In this review we compare and discuss macroscopic transport properties, measured using the straightforward, yet highly powerful technique “modified Ussing chambers”, also denoted side-by-side diffusion cells, for a wide range of structured polymer films and composites. We also discuss and compare the... (More)

Films engineered to control the transport of liquids are widely used through society. Examples include barriers in packaging, wound care products, and controlled release coatings in pharmaceutics. When observed at the macroscopic scale such films commonly appear homogeneous, however, a closer look reveals a complex nano- and microstructure that together with the chemical properties of the different domains control the transport properties. In this review we compare and discuss macroscopic transport properties, measured using the straightforward, yet highly powerful technique “modified Ussing chambers”, also denoted side-by-side diffusion cells, for a wide range of structured polymer films and composites. We also discuss and compare the macroscopic observations and conclusions on materials properties with that of lattice Boltzmann simulations of transport properties based on underlying material structure and chemistry. The survey of the field: (i) highlights the use and power of modified Ussing Chambers for determining liquid transport properties of polymer films, (ii) demonstrates the predictability in both directions between macroscopic observations of transport using modified Ussing chambers and structure-based simulations, and (iii) provides experimental and theoretical insights regarding the transport-determining properties of structured polymer films and composites.

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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Advances in Colloid and Interface Science
volume
256
pages
48 - 64
publisher
Elsevier
external identifiers
  • pmid:29804691
  • scopus:85047408121
ISSN
0001-8686
DOI
10.1016/j.cis.2018.05.004
language
English
LU publication?
yes
id
6c0043ef-e8e2-443c-8ae7-abc7b2610463
date added to LUP
2018-06-07 10:08:28
date last changed
2024-03-18 10:36:16
@article{6c0043ef-e8e2-443c-8ae7-abc7b2610463,
  abstract     = {{<p>Films engineered to control the transport of liquids are widely used through society. Examples include barriers in packaging, wound care products, and controlled release coatings in pharmaceutics. When observed at the macroscopic scale such films commonly appear homogeneous, however, a closer look reveals a complex nano- and microstructure that together with the chemical properties of the different domains control the transport properties. In this review we compare and discuss macroscopic transport properties, measured using the straightforward, yet highly powerful technique “modified Ussing chambers”, also denoted side-by-side diffusion cells, for a wide range of structured polymer films and composites. We also discuss and compare the macroscopic observations and conclusions on materials properties with that of lattice Boltzmann simulations of transport properties based on underlying material structure and chemistry. The survey of the field: (i) highlights the use and power of modified Ussing Chambers for determining liquid transport properties of polymer films, (ii) demonstrates the predictability in both directions between macroscopic observations of transport using modified Ussing chambers and structure-based simulations, and (iii) provides experimental and theoretical insights regarding the transport-determining properties of structured polymer films and composites.</p>}},
  author       = {{Gårdebjer, Sofie and Larsson, Mikael and Gebäck, Tobias and Skepö, Marie and Larsson, Anette}},
  issn         = {{0001-8686}},
  language     = {{eng}},
  month        = {{01}},
  pages        = {{48--64}},
  publisher    = {{Elsevier}},
  series       = {{Advances in Colloid and Interface Science}},
  title        = {{An overview of the transport of liquid molecules through structured polymer films, barriers and composites – Experiments correlated to structure-based simulations}},
  url          = {{http://dx.doi.org/10.1016/j.cis.2018.05.004}},
  doi          = {{10.1016/j.cis.2018.05.004}},
  volume       = {{256}},
  year         = {{2018}},
}