Truncated somatostatin receptor 5 may modulate therapy response to somatostatin analogues - Observations in two patients with acromegaly and severe headache.
(2015) In Growth Hormone & Igf Research 25(5). p.262-267- Abstract
- Somatotropinomas have unique "fingerprints" of somatostatin receptor (sst) expression, which are targets in treatment of acromegaly with somatostatin analogues (SSAs). However, a significant expression of sst is not always related to the biochemical response to SSAs. Headache is a common complaint in acromegaly and considered a clinical marker of disease activity. SSAs are reported to have an own analgesic effect, but the sst involved are unknown.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/7749241
- author
- Marina, Djordje ; Burman, Pia LU ; Klose, Marianne ; Casar-Borota, Olivera ; Luque, Raúl M ; Castaño, Justo P and Feldt-Rasmussen, Ulla
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Growth Hormone & Igf Research
- volume
- 25
- issue
- 5
- pages
- 262 - 267
- publisher
- Elsevier
- external identifiers
-
- pmid:26188991
- wos:000362139000009
- scopus:84941315068
- pmid:26188991
- ISSN
- 1532-2238
- DOI
- 10.1016/j.ghir.2015.07.003
- language
- English
- LU publication?
- yes
- id
- 5a3d29c4-0a7c-4edb-afce-952c34a1672f (old id 7749241)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26188991?dopt=Abstract
- date added to LUP
- 2016-04-01 10:11:36
- date last changed
- 2024-04-07 02:19:10
@article{5a3d29c4-0a7c-4edb-afce-952c34a1672f,
abstract = {{Somatotropinomas have unique "fingerprints" of somatostatin receptor (sst) expression, which are targets in treatment of acromegaly with somatostatin analogues (SSAs). However, a significant expression of sst is not always related to the biochemical response to SSAs. Headache is a common complaint in acromegaly and considered a clinical marker of disease activity. SSAs are reported to have an own analgesic effect, but the sst involved are unknown.}},
author = {{Marina, Djordje and Burman, Pia and Klose, Marianne and Casar-Borota, Olivera and Luque, Raúl M and Castaño, Justo P and Feldt-Rasmussen, Ulla}},
issn = {{1532-2238}},
language = {{eng}},
number = {{5}},
pages = {{262--267}},
publisher = {{Elsevier}},
series = {{Growth Hormone & Igf Research}},
title = {{Truncated somatostatin receptor 5 may modulate therapy response to somatostatin analogues - Observations in two patients with acromegaly and severe headache.}},
url = {{http://dx.doi.org/10.1016/j.ghir.2015.07.003}},
doi = {{10.1016/j.ghir.2015.07.003}},
volume = {{25}},
year = {{2015}},
}