Survival in amoeba-a major selection pressure on the presence of bacterial copper and zinc resistance determinants? Identification of a "copper pathogenicity island"
(2015) In Applied Microbiology and Biotechnology 99(14). p.5817-5824- Abstract
- The presence of metal resistance determinants in bacteria usually is attributed to geological or anthropogenic metal contamination in different environments or associated with the use of antimicrobial metals in human healthcare or in agriculture. While this is certainly true, we hypothesize that protozoan predation and macrophage killing are also responsible for selection of copper/zinc resistance genes in bacteria. In this review, we outline evidence supporting this hypothesis, as well as highlight the correlation between metal resistance and pathogenicity in bacteria. In addition, we introduce and characterize the "copper pathogenicity island" identified in Escherichia coli and Salmonella strains isolated from copper- and zinc-fed Danish... (More)
- The presence of metal resistance determinants in bacteria usually is attributed to geological or anthropogenic metal contamination in different environments or associated with the use of antimicrobial metals in human healthcare or in agriculture. While this is certainly true, we hypothesize that protozoan predation and macrophage killing are also responsible for selection of copper/zinc resistance genes in bacteria. In this review, we outline evidence supporting this hypothesis, as well as highlight the correlation between metal resistance and pathogenicity in bacteria. In addition, we introduce and characterize the "copper pathogenicity island" identified in Escherichia coli and Salmonella strains isolated from copper- and zinc-fed Danish pigs. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/7791035
- author
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Copper, Pathogenicity, Amoeba, Grazing resistance
- in
- Applied Microbiology and Biotechnology
- volume
- 99
- issue
- 14
- pages
- 5817 - 5824
- publisher
- Springer
- external identifiers
-
- wos:000356806300005
- scopus:84932196151
- pmid:26088177
- ISSN
- 1432-0614
- DOI
- 10.1007/s00253-015-6749-0
- language
- English
- LU publication?
- yes
- id
- 6e92ebbd-7032-4a99-a019-34d485199096 (old id 7791035)
- date added to LUP
- 2016-04-01 14:42:57
- date last changed
- 2022-02-19 20:25:04
@article{6e92ebbd-7032-4a99-a019-34d485199096,
abstract = {{The presence of metal resistance determinants in bacteria usually is attributed to geological or anthropogenic metal contamination in different environments or associated with the use of antimicrobial metals in human healthcare or in agriculture. While this is certainly true, we hypothesize that protozoan predation and macrophage killing are also responsible for selection of copper/zinc resistance genes in bacteria. In this review, we outline evidence supporting this hypothesis, as well as highlight the correlation between metal resistance and pathogenicity in bacteria. In addition, we introduce and characterize the "copper pathogenicity island" identified in Escherichia coli and Salmonella strains isolated from copper- and zinc-fed Danish pigs.}},
author = {{Hao, Xiuli and Luethje, Freja L. and Qin, Yanan and McDevitt, Sylvia Franke and Lutay, Nataliya and Hobman, Jon L. and Asiani, Karishma and Soncini, Fernando C. and German, Nadezhda and Zhang, Siyu and Zhu, Yong-Guan and Rensing, Christopher}},
issn = {{1432-0614}},
keywords = {{Copper; Pathogenicity; Amoeba; Grazing resistance}},
language = {{eng}},
number = {{14}},
pages = {{5817--5824}},
publisher = {{Springer}},
series = {{Applied Microbiology and Biotechnology}},
title = {{Survival in amoeba-a major selection pressure on the presence of bacterial copper and zinc resistance determinants? Identification of a "copper pathogenicity island"}},
url = {{http://dx.doi.org/10.1007/s00253-015-6749-0}},
doi = {{10.1007/s00253-015-6749-0}},
volume = {{99}},
year = {{2015}},
}