Airway responsiveness to mannitol in asthma is associated with chymase-positive mast cells and eosinophilic airway inflammation.
(2016) In Clinical and Experimental Allergy 46(2). p.288-297- Abstract
- Airway hyperresponsiveness (AHR) to inhaled mannitol is associated with indirect markers of mast cell activation and eosinophilic airway inflammation. It is unknown how AHR to mannitol relates to mast cell phenotype, mast cell function and measures of eosinophilic inflammation in airway tissue. We compared the number and phenotype of mast cells, mRNA expression of mast cell associated genes and number of eosinophils in airway tissue of subjects with asthma and healthy controls in relation to AHR to mannitol.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/7844404
- author
- Sverrild, Asger ; Bergqvist, Anders LU ; Baines, Katherine J ; Porsbjerg, Celeste ; Andersson, Cecilia LU ; Thomsen, Simon Francis ; Hoffmann, Hans Jürgen ; Gibson, Peter ; Erjefält, Jonas LU and Backer, Vibeke
- organization
- publishing date
- 2016
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Clinical and Experimental Allergy
- volume
- 46
- issue
- 2
- pages
- 288 - 297
- publisher
- Wiley
- external identifiers
-
- pmid:26252943
- scopus:84955597145
- wos:000370057800007
- pmid:26252943
- ISSN
- 1365-2222
- DOI
- 10.1111/cea.12609
- language
- English
- LU publication?
- yes
- id
- 899e97fe-150c-4355-a31f-361ce9eedbd2 (old id 7844404)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26252943?dopt=Abstract
- date added to LUP
- 2016-04-04 08:48:54
- date last changed
- 2022-02-20 22:12:31
@article{899e97fe-150c-4355-a31f-361ce9eedbd2, abstract = {{Airway hyperresponsiveness (AHR) to inhaled mannitol is associated with indirect markers of mast cell activation and eosinophilic airway inflammation. It is unknown how AHR to mannitol relates to mast cell phenotype, mast cell function and measures of eosinophilic inflammation in airway tissue. We compared the number and phenotype of mast cells, mRNA expression of mast cell associated genes and number of eosinophils in airway tissue of subjects with asthma and healthy controls in relation to AHR to mannitol.}}, author = {{Sverrild, Asger and Bergqvist, Anders and Baines, Katherine J and Porsbjerg, Celeste and Andersson, Cecilia and Thomsen, Simon Francis and Hoffmann, Hans Jürgen and Gibson, Peter and Erjefält, Jonas and Backer, Vibeke}}, issn = {{1365-2222}}, language = {{eng}}, number = {{2}}, pages = {{288--297}}, publisher = {{Wiley}}, series = {{Clinical and Experimental Allergy}}, title = {{Airway responsiveness to mannitol in asthma is associated with chymase-positive mast cells and eosinophilic airway inflammation.}}, url = {{http://dx.doi.org/10.1111/cea.12609}}, doi = {{10.1111/cea.12609}}, volume = {{46}}, year = {{2016}}, }