Saliva S100B in professional sportsmen: High levels at resting conditions and increased after vigorous physical activity
(2011) In Clinical Biochemistry 44(2-3). p.245-247- Abstract
- Background: Neurological dysfunction is a key medical concern in professional sportsmen (PSM). We investigated whether saliva S100B concentrations in PSM and healthy controls are modified before and after training. Methods: We conducted a case-control-study in 75 patients (25 PSM vs 50 controls) in which S100B saliva concentrations were expressed as absolute values and percentage of change (%) from samples drawn before (T0) and after (T1) training. Results: No differences (P>0.05) between groups were found regarding clinical, monitoring and laboratory parameters. S100B both in PSM and controls was higher at T1 when compared to TO (P<0.01). In PSM, S100B was higher than controls (P<0.001) at TO and T1. S100B% at T0-T1 was higher... (More)
- Background: Neurological dysfunction is a key medical concern in professional sportsmen (PSM). We investigated whether saliva S100B concentrations in PSM and healthy controls are modified before and after training. Methods: We conducted a case-control-study in 75 patients (25 PSM vs 50 controls) in which S100B saliva concentrations were expressed as absolute values and percentage of change (%) from samples drawn before (T0) and after (T1) training. Results: No differences (P>0.05) between groups were found regarding clinical, monitoring and laboratory parameters. S100B both in PSM and controls was higher at T1 when compared to TO (P<0.01). In PSM, S100B was higher than controls (P<0.001) at TO and T1. S100B% at T0-T1 was higher (P<0.001) in PSM and in controls and between PSM and controls (P<0.001). Conclusions: Increased saliva S100B levels in PSM before and after training suggest a paracrine/autocrine protein's role connected to stressing activity, which becomes especially evident in PSMs. (C) 2010 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved. (Less)
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https://lup.lub.lu.se/record/7855486
- author
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Neurodegenerative disorders, Saliva, S100B protein, Sport
- in
- Clinical Biochemistry
- volume
- 44
- issue
- 2-3
- pages
- 245 - 247
- publisher
- Elsevier
- external identifiers
-
- wos:000286959100018
- scopus:79151480512
- pmid:20970414
- ISSN
- 1873-2933
- DOI
- 10.1016/j.clinbiochem.2010.10.007
- language
- English
- LU publication?
- no
- id
- 5a294f45-2647-4600-9fc1-df3bb44936cc (old id 7855486)
- date added to LUP
- 2016-04-01 10:50:30
- date last changed
- 2022-02-25 06:07:46
@article{5a294f45-2647-4600-9fc1-df3bb44936cc, abstract = {{Background: Neurological dysfunction is a key medical concern in professional sportsmen (PSM). We investigated whether saliva S100B concentrations in PSM and healthy controls are modified before and after training. Methods: We conducted a case-control-study in 75 patients (25 PSM vs 50 controls) in which S100B saliva concentrations were expressed as absolute values and percentage of change (%) from samples drawn before (T0) and after (T1) training. Results: No differences (P>0.05) between groups were found regarding clinical, monitoring and laboratory parameters. S100B both in PSM and controls was higher at T1 when compared to TO (P<0.01). In PSM, S100B was higher than controls (P<0.001) at TO and T1. S100B% at T0-T1 was higher (P<0.001) in PSM and in controls and between PSM and controls (P<0.001). Conclusions: Increased saliva S100B levels in PSM before and after training suggest a paracrine/autocrine protein's role connected to stressing activity, which becomes especially evident in PSMs. (C) 2010 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.}}, author = {{Michetti, Fabrizio and Bruschettini, Matteo and Frigiola, Alessandro and Abella, Raul and Giamberti, Alessandro and Marchese, Nora and Mangraviti, Salvatore and Melioli, Giovanni and Baldari, Amedeo and Bruschettini, Pierluigi and Gazzolo, Diego}}, issn = {{1873-2933}}, keywords = {{Neurodegenerative disorders; Saliva; S100B protein; Sport}}, language = {{eng}}, number = {{2-3}}, pages = {{245--247}}, publisher = {{Elsevier}}, series = {{Clinical Biochemistry}}, title = {{Saliva S100B in professional sportsmen: High levels at resting conditions and increased after vigorous physical activity}}, url = {{http://dx.doi.org/10.1016/j.clinbiochem.2010.10.007}}, doi = {{10.1016/j.clinbiochem.2010.10.007}}, volume = {{44}}, year = {{2011}}, }