eGFR, cystatin C and creatinine in shrunken pore syndrome
(2019) In Clinica Chimica Acta 498(Nov). p.1-5- Abstract
Shrunken pore syndrome (SPS) is a condition in which the estimated glomerular filtration rate (eGFR) based on serum/plasma cystatin C concentration is significantly lower than the eGFR based on creatinine. According to the literatures, the diagnosis of SPS could be defined when the eGFRcystatin C is <70% of eGFRcreatinine. Although the incidence of SPS varies in different patient populations and healthy seniors, it has been demonstrated that patients with SPS have poor prognosis. The present review has summarized its diagnosis, epidemiology, prognosis and possible pathophysiology basis. Moreover, we discuss the prevention and treatment of SPS in clinical practice as future challenges.
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https://lup.lub.lu.se/record/7dce4221-4712-484b-a04b-52a520e346bd
- author
- Zhou, Hua ; Yang, Min ; He, Xiaozhou and Xu, Ning LU
- organization
- publishing date
- 2019
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Creatinine, Cystatin C, Glomerular filtration rate, Shrunken pore syndrome
- in
- Clinica Chimica Acta
- volume
- 498
- issue
- Nov
- pages
- 5 pages
- publisher
- Elsevier
- external identifiers
-
- scopus:85070267771
- pmid:31398310
- ISSN
- 0009-8981
- DOI
- 10.1016/j.cca.2019.08.001
- language
- English
- LU publication?
- yes
- id
- 7dce4221-4712-484b-a04b-52a520e346bd
- date added to LUP
- 2019-08-29 13:03:32
- date last changed
- 2024-08-07 04:28:41
@article{7dce4221-4712-484b-a04b-52a520e346bd, abstract = {{<p>Shrunken pore syndrome (SPS) is a condition in which the estimated glomerular filtration rate (eGFR) based on serum/plasma cystatin C concentration is significantly lower than the eGFR based on creatinine. According to the literatures, the diagnosis of SPS could be defined when the eGFR<sub>cystatin C</sub> is <70% of eGFR<sub>creatinine</sub>. Although the incidence of SPS varies in different patient populations and healthy seniors, it has been demonstrated that patients with SPS have poor prognosis. The present review has summarized its diagnosis, epidemiology, prognosis and possible pathophysiology basis. Moreover, we discuss the prevention and treatment of SPS in clinical practice as future challenges.</p>}}, author = {{Zhou, Hua and Yang, Min and He, Xiaozhou and Xu, Ning}}, issn = {{0009-8981}}, keywords = {{Creatinine; Cystatin C; Glomerular filtration rate; Shrunken pore syndrome}}, language = {{eng}}, number = {{Nov}}, pages = {{1--5}}, publisher = {{Elsevier}}, series = {{Clinica Chimica Acta}}, title = {{eGFR, cystatin C and creatinine in shrunken pore syndrome}}, url = {{http://dx.doi.org/10.1016/j.cca.2019.08.001}}, doi = {{10.1016/j.cca.2019.08.001}}, volume = {{498}}, year = {{2019}}, }