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Enhetliga analyser av narkotika i urin krävs för rättssäkerheten.

Hansson, Therese LU ; Helander, Anders ; Beck, Olof ; Elmgren, Anders ; Kugelberg, Fredrik and Kronstrand, Robert (2015) In Läkartidningen 112.
Abstract
Drugs of abuse testing is used in various areas of society for detection and follow-up of drug use. In routine laboratory drug testing, immunoassays are employed for initial screening of specimens to indicate the presence of drugs. To confirm a positive screening test, a secondary analysis by mass spectrometry is performed. The »cut-off« is the pre-defined concentration threshold of a drug or drug metabolite above which the sample is considered positive. A reading below this level implies a negative test result. Swedish drug testing laboratories currently employ varying cut-offs to distinguish between a positive and a negative test result. Because a positive drug test may have serious legal consequences to the individual, it is of... (More)
Drugs of abuse testing is used in various areas of society for detection and follow-up of drug use. In routine laboratory drug testing, immunoassays are employed for initial screening of specimens to indicate the presence of drugs. To confirm a positive screening test, a secondary analysis by mass spectrometry is performed. The »cut-off« is the pre-defined concentration threshold of a drug or drug metabolite above which the sample is considered positive. A reading below this level implies a negative test result. Swedish drug testing laboratories currently employ varying cut-offs to distinguish between a positive and a negative test result. Because a positive drug test may have serious legal consequences to the individual, it is of importance that testing is performed and judged equally, regardless of where it is performed. A national harmonization of cut-offs is therefore warranted. Based on data from four major Swedish drug testing laboratories, and considering the recommendations in international guidelines, a proposal for national harmonization of urine cut-offs for the most common set of drugs of abuse is presented. (Less)
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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Läkartidningen
volume
112
publisher
Swedish Medical Association
external identifiers
  • pmid:26393972
  • scopus:84942092615
ISSN
0023-7205
language
Swedish
LU publication?
yes
id
ba7318a5-413f-4ce3-93f6-9351b630424b (old id 8035353)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26393972?dopt=Abstract
http://www.lakartidningen.se/Klinik-och-vetenskap/Klinisk-oversikt/2015/09/Enhetliga-analyser-av-narkotika-i-urin-kravs-for-rattssakerheten/
date added to LUP
2016-04-04 09:39:35
date last changed
2022-01-29 18:54:15
@article{ba7318a5-413f-4ce3-93f6-9351b630424b,
  abstract     = {{Drugs of abuse testing is used in various areas of society for detection and follow-up of drug use. In routine laboratory drug testing, immunoassays are employed for initial screening of specimens to indicate the presence of drugs. To confirm a positive screening test, a secondary analysis by mass spectrometry is performed. The »cut-off« is the pre-defined concentration threshold of a drug or drug metabolite above which the sample is considered positive. A reading below this level implies a negative test result. Swedish drug testing laboratories currently employ varying cut-offs to distinguish between a positive and a negative test result. Because a positive drug test may have serious legal consequences to the individual, it is of importance that testing is performed and judged equally, regardless of where it is performed. A national harmonization of cut-offs is therefore warranted. Based on data from four major Swedish drug testing laboratories, and considering the recommendations in international guidelines, a proposal for national harmonization of urine cut-offs for the most common set of drugs of abuse is presented.}},
  author       = {{Hansson, Therese and Helander, Anders and Beck, Olof and Elmgren, Anders and Kugelberg, Fredrik and Kronstrand, Robert}},
  issn         = {{0023-7205}},
  language     = {{swe}},
  publisher    = {{Swedish Medical Association}},
  series       = {{Läkartidningen}},
  title        = {{Enhetliga analyser av narkotika i urin krävs för rättssäkerheten.}},
  url          = {{http://www.ncbi.nlm.nih.gov/pubmed/26393972?dopt=Abstract}},
  volume       = {{112}},
  year         = {{2015}},
}