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Heparin-Binding Protein Measurement Improves the Prediction of Severe Infection With Organ Dysfunction in the Emergency Department.

Linder, Adam LU ; Arnold, Ryan ; Boyd, John H ; Zindovic, Marko ; Zindovic, Igor LU ; Lange, Anna ; Paulsson, Magnus LU orcid ; Nyberg, Patrik LU ; Russell, James A and Pritchard, David , et al. (2015) In Critical Care Medicine 43(11). p.2378-2386
Abstract
Early identification of patients with infection and at risk of developing severe disease with organ dysfunction remains a difficult challenge. We aimed to evaluate and validate the heparin-binding protein, a neutrophil-derived mediator of vascular leakage, as a prognostic biomarker for risk of progression to severe sepsis with circulatory failure in a multicenter setting.
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Critical Care Medicine
volume
43
issue
11
pages
2378 - 2386
publisher
Lippincott Williams & Wilkins
external identifiers
  • pmid:26468696
  • wos:000362826200014
  • scopus:84944448352
  • pmid:26468696
ISSN
1530-0293
DOI
10.1097/CCM.0000000000001265
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Thoracic Surgery (013230027), Faculty of Medicine (000022000), Clinical Microbiology, Malmö (013011000), Division of Infection Medicine (SUS) (013008000)
id
aa529a3d-0ddc-45da-b614-03cb3a0b96e7 (old id 8152212)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26468696?dopt=Abstract
date added to LUP
2016-04-01 10:17:35
date last changed
2022-04-20 00:31:09
@article{aa529a3d-0ddc-45da-b614-03cb3a0b96e7,
  abstract     = {{Early identification of patients with infection and at risk of developing severe disease with organ dysfunction remains a difficult challenge. We aimed to evaluate and validate the heparin-binding protein, a neutrophil-derived mediator of vascular leakage, as a prognostic biomarker for risk of progression to severe sepsis with circulatory failure in a multicenter setting.}},
  author       = {{Linder, Adam and Arnold, Ryan and Boyd, John H and Zindovic, Marko and Zindovic, Igor and Lange, Anna and Paulsson, Magnus and Nyberg, Patrik and Russell, James A and Pritchard, David and Christensson, Bertil and Åkesson, Per}},
  issn         = {{1530-0293}},
  language     = {{eng}},
  number       = {{11}},
  pages        = {{2378--2386}},
  publisher    = {{Lippincott Williams & Wilkins}},
  series       = {{Critical Care Medicine}},
  title        = {{Heparin-Binding Protein Measurement Improves the Prediction of Severe Infection With Organ Dysfunction in the Emergency Department.}},
  url          = {{http://dx.doi.org/10.1097/CCM.0000000000001265}},
  doi          = {{10.1097/CCM.0000000000001265}},
  volume       = {{43}},
  year         = {{2015}},
}