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Treatment costs for advanced prostate cancer using luteinizing hormone-releasing hormone agonists: a solid biodegradable leuprorelin implant versus other formulations

Merseburger, Axel S. ; Björk, Thomas LU ; Whitehouse, James and Meani, Davide (2015) In Journal of Comparative Effectiveness Research 4(5). p.447-453
Abstract
Aim: To compare treatment costs with alternative luteinizing hormone-releasing hormone (LHRH) agonist preparations and determine whether a leuprorelin solid implant is associated with potential cost savings. Patients & methods: A hypothetical population of 1000 prostate cancer patients was apportioned between the three most commonly-prescribed LHRH agonist preparations. Differentiated annual costs for 1- and 3-monthly formulations were calculated for France, Germany, Italy, Spain, the UK (EU5) and Sweden, and compared with the leuprorelin solid implant. Results: Compared with alternative formulations, leuprorelin solid implants had potential annual cost savings/1000 patients of Euro353,000 (EU5) and Euro699,000 (Sweden; 1-month... (More)
Aim: To compare treatment costs with alternative luteinizing hormone-releasing hormone (LHRH) agonist preparations and determine whether a leuprorelin solid implant is associated with potential cost savings. Patients & methods: A hypothetical population of 1000 prostate cancer patients was apportioned between the three most commonly-prescribed LHRH agonist preparations. Differentiated annual costs for 1- and 3-monthly formulations were calculated for France, Germany, Italy, Spain, the UK (EU5) and Sweden, and compared with the leuprorelin solid implant. Results: Compared with alternative formulations, leuprorelin solid implants had potential annual cost savings/1000 patients of Euro353,000 (EU5) and Euro699,000 (Sweden; 1-month formulations), and Euro259,000 (EU5) and Euro300,000 (Sweden; 3-month formulations). Conclusion: The leuprorelin solid implant was associated with potential cost savings compared with the most commonly used LHRH agonist preparations. (Less)
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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
costs, economics, leuprorelin, luteinizing hormone-releasing hormone, agonists, prostate cancer
in
Journal of Comparative Effectiveness Research
volume
4
issue
5
pages
447 - 453
publisher
Future Medicine Ltd.
external identifiers
  • wos:000363397600003
  • scopus:84945321592
  • pmid:25521079
ISSN
2042-6305
DOI
10.2217/cer.14.82
language
English
LU publication?
yes
id
41374421-0476-4e7a-85a1-5e8720ae1290 (old id 8201713)
date added to LUP
2016-04-01 14:56:32
date last changed
2022-04-30 05:15:08
@article{41374421-0476-4e7a-85a1-5e8720ae1290,
  abstract     = {{Aim: To compare treatment costs with alternative luteinizing hormone-releasing hormone (LHRH) agonist preparations and determine whether a leuprorelin solid implant is associated with potential cost savings. Patients & methods: A hypothetical population of 1000 prostate cancer patients was apportioned between the three most commonly-prescribed LHRH agonist preparations. Differentiated annual costs for 1- and 3-monthly formulations were calculated for France, Germany, Italy, Spain, the UK (EU5) and Sweden, and compared with the leuprorelin solid implant. Results: Compared with alternative formulations, leuprorelin solid implants had potential annual cost savings/1000 patients of Euro353,000 (EU5) and Euro699,000 (Sweden; 1-month formulations), and Euro259,000 (EU5) and Euro300,000 (Sweden; 3-month formulations). Conclusion: The leuprorelin solid implant was associated with potential cost savings compared with the most commonly used LHRH agonist preparations.}},
  author       = {{Merseburger, Axel S. and Björk, Thomas and Whitehouse, James and Meani, Davide}},
  issn         = {{2042-6305}},
  keywords     = {{costs; economics; leuprorelin; luteinizing hormone-releasing hormone; agonists; prostate cancer}},
  language     = {{eng}},
  number       = {{5}},
  pages        = {{447--453}},
  publisher    = {{Future Medicine Ltd.}},
  series       = {{Journal of Comparative Effectiveness Research}},
  title        = {{Treatment costs for advanced prostate cancer using luteinizing hormone-releasing hormone agonists: a solid biodegradable leuprorelin implant versus other formulations}},
  url          = {{http://dx.doi.org/10.2217/cer.14.82}},
  doi          = {{10.2217/cer.14.82}},
  volume       = {{4}},
  year         = {{2015}},
}