Short-term adaptation during propagation improves the performance of xylose-fermenting Saccharomyces cerevisiae in simultaneous saccharification and co-fermentation.
Nielsen, Fredrik LU ; Tomás-Pejó, Elia ; Olsson, Lisbeth and Wallberg, Ola LU
(2015)
In Biotechnology for Biofuels
8.
- Abstract
- Inhibitors that are generated during thermochemical pretreatment and hydrolysis impair the performance of microorganisms during fermentation of lignocellulosic hydrolysates. In omitting costly detoxification steps, the fermentation process relies extensively on the performance of the fermenting microorganism. One attractive option of improving its performance and tolerance to microbial inhibitors is short-term adaptation during propagation. This study determined the influence of short-term adaptation on the performance of recombinant Saccharomyces cerevisiae in simultaneous saccharification and co-fermentation (SSCF). The aim was to understand how short-term adaptation with lignocellulosic hydrolysate affects the cell mass yield of... (More)
- Inhibitors that are generated during thermochemical pretreatment and hydrolysis impair the performance of microorganisms during fermentation of lignocellulosic hydrolysates. In omitting costly detoxification steps, the fermentation process relies extensively on the performance of the fermenting microorganism. One attractive option of improving its performance and tolerance to microbial inhibitors is short-term adaptation during propagation. This study determined the influence of short-term adaptation on the performance of recombinant Saccharomyces cerevisiae in simultaneous saccharification and co-fermentation (SSCF). The aim was to understand how short-term adaptation with lignocellulosic hydrolysate affects the cell mass yield of propagated yeast and performance in subsequent fermentation steps. The physiology of propagated yeast was examined with regard to viability, vitality, stress responses, and upregulation of relevant genes to identify any links between the beneficial traits that are promoted during adaptation and overall ethanol yields in co-fermentation. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8503848
- author
- Nielsen, Fredrik
LU
; Tomás-Pejó, Elia
; Olsson, Lisbeth
and Wallberg, Ola
LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Biotechnology for Biofuels
- volume
- 8
- article number
- 219
- publisher
- BioMed Central (BMC)
- external identifiers
-
- pmid:26697108
- wos:000367227500003
- scopus:84954075853
- pmid:26697108
- ISSN
- 1754-6834
- DOI
- 10.1186/s13068-015-0399-4
- language
- English
- LU publication?
- yes
- id
- 42e35f23-4355-496d-9e6c-744b92b7aa48 (old id 8503848)
- date added to LUP
- 2016-04-01 14:45:54
- date last changed
- 2023-12-12 09:49:56
@article{42e35f23-4355-496d-9e6c-744b92b7aa48,
abstract = {{Inhibitors that are generated during thermochemical pretreatment and hydrolysis impair the performance of microorganisms during fermentation of lignocellulosic hydrolysates. In omitting costly detoxification steps, the fermentation process relies extensively on the performance of the fermenting microorganism. One attractive option of improving its performance and tolerance to microbial inhibitors is short-term adaptation during propagation. This study determined the influence of short-term adaptation on the performance of recombinant Saccharomyces cerevisiae in simultaneous saccharification and co-fermentation (SSCF). The aim was to understand how short-term adaptation with lignocellulosic hydrolysate affects the cell mass yield of propagated yeast and performance in subsequent fermentation steps. The physiology of propagated yeast was examined with regard to viability, vitality, stress responses, and upregulation of relevant genes to identify any links between the beneficial traits that are promoted during adaptation and overall ethanol yields in co-fermentation.}},
author = {{Nielsen, Fredrik and Tomás-Pejó, Elia and Olsson, Lisbeth and Wallberg, Ola}},
issn = {{1754-6834}},
language = {{eng}},
publisher = {{BioMed Central (BMC)}},
series = {{Biotechnology for Biofuels}},
title = {{Short-term adaptation during propagation improves the performance of xylose-fermenting Saccharomyces cerevisiae in simultaneous saccharification and co-fermentation.}},
url = {{http://dx.doi.org/10.1186/s13068-015-0399-4}},
doi = {{10.1186/s13068-015-0399-4}},
volume = {{8}},
year = {{2015}},
}