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Plasma Levels of Neopterin and C-Reactive Protein (CRP) in Tuberculosis (TB) with and without HIV Coinfection in Relation to CD4 Cell Count.

Skogmar, Sten LU ; Schön, Thomas ; Balcha, Taye LU ; Sturegård, Erik LU ; Jansson, Marianne LU and Björkman, Per LU orcid (2015) In PLoS ONE 10(12).
Abstract
While the risk of TB is elevated in HIV-positive subjects with low CD4 cell counts, TB may in itself be associated with CD4 lymphocytopenia. We investigated markers of immune activation (neopterin) and inflammation (CRP) in TB patients with and without HIV coinfection and their association with CD4 cell levels, and determined their predictive capacity as alternative markers of advanced immunosuppression.
Please use this url to cite or link to this publication:
author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
PLoS ONE
volume
10
issue
12
article number
e0144292
publisher
Public Library of Science (PLoS)
external identifiers
  • pmid:26630153
  • wos:000365926300176
  • scopus:84955592844
  • pmid:26630153
ISSN
1932-6203
DOI
10.1371/journal.pone.0144292
language
English
LU publication?
yes
id
432fec30-9173-4ef1-886b-932f81c673e7 (old id 8505766)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26630153?dopt=Abstract
date added to LUP
2016-04-01 14:04:04
date last changed
2022-05-19 22:33:55
@article{432fec30-9173-4ef1-886b-932f81c673e7,
  abstract     = {{While the risk of TB is elevated in HIV-positive subjects with low CD4 cell counts, TB may in itself be associated with CD4 lymphocytopenia. We investigated markers of immune activation (neopterin) and inflammation (CRP) in TB patients with and without HIV coinfection and their association with CD4 cell levels, and determined their predictive capacity as alternative markers of advanced immunosuppression.}},
  author       = {{Skogmar, Sten and Schön, Thomas and Balcha, Taye and Sturegård, Erik and Jansson, Marianne and Björkman, Per}},
  issn         = {{1932-6203}},
  language     = {{eng}},
  number       = {{12}},
  publisher    = {{Public Library of Science (PLoS)}},
  series       = {{PLoS ONE}},
  title        = {{Plasma Levels of Neopterin and C-Reactive Protein (CRP) in Tuberculosis (TB) with and without HIV Coinfection in Relation to CD4 Cell Count.}},
  url          = {{http://dx.doi.org/10.1371/journal.pone.0144292}},
  doi          = {{10.1371/journal.pone.0144292}},
  volume       = {{10}},
  year         = {{2015}},
}