Kynurenic acid modulates experimentally induced inflammation in the trigeminal ganglion.
(2015) In Journal of Headache and Pain 16(99).- Abstract
- The trigeminal ganglion (TG) plays a central role in cranial pain. Administration of complete Freund's adjuvant (CFA) into the temporomandibular joint (TMJ) elicits activation of TG. Kynurenic acid (KYNA) is an endogenous excitatory amino acid receptor blocker, which may have an anti-inflammatory effect. We hypothesize that KYNA may reduce CFA-induced activation within the TG.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8505868
- author
- Csáti, A ; Edvinsson, Lars LU ; Vécsei, L ; Toldi, J ; Fülöp, F ; Tajti, J and Warfvinge, Karin LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Headache and Pain
- volume
- 16
- issue
- 99
- article number
- 99
- publisher
- Springer
- external identifiers
-
- pmid:26627709
- wos:000368626000001
- scopus:84948955616
- pmid:26627709
- ISSN
- 1129-2369
- DOI
- 10.1186/s10194-015-0581-x
- language
- English
- LU publication?
- yes
- id
- 53690eb8-820c-46eb-bba1-9d99605c9516 (old id 8505868)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26627709?dopt=Abstract
- date added to LUP
- 2016-04-01 10:45:19
- date last changed
- 2024-01-07 00:21:48
@article{53690eb8-820c-46eb-bba1-9d99605c9516, abstract = {{The trigeminal ganglion (TG) plays a central role in cranial pain. Administration of complete Freund's adjuvant (CFA) into the temporomandibular joint (TMJ) elicits activation of TG. Kynurenic acid (KYNA) is an endogenous excitatory amino acid receptor blocker, which may have an anti-inflammatory effect. We hypothesize that KYNA may reduce CFA-induced activation within the TG.}}, author = {{Csáti, A and Edvinsson, Lars and Vécsei, L and Toldi, J and Fülöp, F and Tajti, J and Warfvinge, Karin}}, issn = {{1129-2369}}, language = {{eng}}, number = {{99}}, publisher = {{Springer}}, series = {{Journal of Headache and Pain}}, title = {{Kynurenic acid modulates experimentally induced inflammation in the trigeminal ganglion.}}, url = {{http://dx.doi.org/10.1186/s10194-015-0581-x}}, doi = {{10.1186/s10194-015-0581-x}}, volume = {{16}}, year = {{2015}}, }