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Insulin-like growth factor 1 has multisystem effects on fetal and preterm infant development.

Hellström, Ann ; Ley, David LU ; Pupp, Ingrid LU orcid ; Hallberg, Boubou ; Löfqvist, Chatarina ; van Marter, Linda ; van Weissenbruch, Mirjam ; Ramenghi, Luca A ; Beardsall, Kathryn and Dunger, David , et al. (2016) In Acta paediatrica 105(6). p.576-586
Abstract
Poor postnatal growth after preterm birth does not match the normal rapid growth in utero and is associated with preterm morbidities. Insulin-like growth factor 1 (IGF-1) axis is the major hormonal mediator of growth in utero and levels of IGF-1 are often very low after preterm birth. We reviewed the role of IGF-1 in fetal development and the corresponding preterm perinatal period to highlight the potential clinical importance of IGF-1 deficiency in preterm morbidities.
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta paediatrica
volume
105
issue
6
pages
576 - 586
publisher
Wiley-Blackwell
external identifiers
  • pmid:26833743
  • scopus:84960153731
  • pmid:26833743
  • wos:000376265400012
ISSN
1651-2227
DOI
10.1111/apa.13350
language
English
LU publication?
yes
id
e849d1dd-474d-4e4a-a29b-4bf55cf547c8 (old id 8829508)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26833743?dopt=Abstract
date added to LUP
2016-04-01 13:36:22
date last changed
2024-02-25 01:03:38
@article{e849d1dd-474d-4e4a-a29b-4bf55cf547c8,
  abstract     = {{Poor postnatal growth after preterm birth does not match the normal rapid growth in utero and is associated with preterm morbidities. Insulin-like growth factor 1 (IGF-1) axis is the major hormonal mediator of growth in utero and levels of IGF-1 are often very low after preterm birth. We reviewed the role of IGF-1 in fetal development and the corresponding preterm perinatal period to highlight the potential clinical importance of IGF-1 deficiency in preterm morbidities.}},
  author       = {{Hellström, Ann and Ley, David and Pupp, Ingrid and Hallberg, Boubou and Löfqvist, Chatarina and van Marter, Linda and van Weissenbruch, Mirjam and Ramenghi, Luca A and Beardsall, Kathryn and Dunger, David and Hård, Anna-Lena and Smith, Lois E H}},
  issn         = {{1651-2227}},
  language     = {{eng}},
  month        = {{02}},
  number       = {{6}},
  pages        = {{576--586}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Acta paediatrica}},
  title        = {{Insulin-like growth factor 1 has multisystem effects on fetal and preterm infant development.}},
  url          = {{http://dx.doi.org/10.1111/apa.13350}},
  doi          = {{10.1111/apa.13350}},
  volume       = {{105}},
  year         = {{2016}},
}