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Results of second-look resection after primary resection of T1 tumour of the urinary bladder

Jahnson, S ; Wiklund, F ; Duchek, M ; Mestad, O ; Rintala, E ; Hellsten, Sverker LU and Malmstrom, PU (2005) In Scandinavian Journal of Urology and Nephrology 39(3). p.206-210
Abstract
Objective. To study residual tumours at second-look resection in patients resected 4-8 weeks earlier for T1 tumours of the urinary bladder. Material and methods. All patients randomized in the ongoing Nordic T1G2-G3 Bladder Sparing Study with monitored data available were included in the study. Data on residual tumours at second-look resection were compared to basic patient and tumour characteristics. Results. There were 72 patients (56%) without and 57 with residual exophytic tumours. In the former group, 20 patients (28%) had carcinoma in situ, compared to 19 (33%) in the latter group. Potentially dangerous tumours (either carcinoma in situ, T1 or Ta grade 3) were observed in 55 patients (43%). Multiple tumours at primary resection were... (More)
Objective. To study residual tumours at second-look resection in patients resected 4-8 weeks earlier for T1 tumours of the urinary bladder. Material and methods. All patients randomized in the ongoing Nordic T1G2-G3 Bladder Sparing Study with monitored data available were included in the study. Data on residual tumours at second-look resection were compared to basic patient and tumour characteristics. Results. There were 72 patients (56%) without and 57 with residual exophytic tumours. In the former group, 20 patients (28%) had carcinoma in situ, compared to 19 (33%) in the latter group. Potentially dangerous tumours (either carcinoma in situ, T1 or Ta grade 3) were observed in 55 patients (43%). Multiple tumours at primary resection were more prone to residual tumour at second-look resection than single tumours. No other tumour or patient characteristics could predict the occurrence of a residual tumour. Conclusions. Residual tumours are frequently observed at second-look resection 4-8 weeks after primary resection of T1 tumours. The majority of residual tumours detected at this stage are potentially dangerous; therefore, early second-look resection followed by intravesical instillation therapy is mandatory in patients with T1 tumours of the urinary bladder. (Less)
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author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
bladder cancer, primary resection, second-look resection
in
Scandinavian Journal of Urology and Nephrology
volume
39
issue
3
pages
206 - 210
publisher
Taylor & Francis
external identifiers
  • wos:000230486700004
  • pmid:16127800
  • scopus:22144450372
ISSN
0036-5599
DOI
10.1080/00365590510007793
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Urology (013243400)
id
2cba81cd-188e-402f-9104-c3d7d90ae4b1 (old id 895030)
date added to LUP
2016-04-01 16:11:57
date last changed
2022-01-28 18:01:18
@article{2cba81cd-188e-402f-9104-c3d7d90ae4b1,
  abstract     = {{Objective. To study residual tumours at second-look resection in patients resected 4-8 weeks earlier for T1 tumours of the urinary bladder. Material and methods. All patients randomized in the ongoing Nordic T1G2-G3 Bladder Sparing Study with monitored data available were included in the study. Data on residual tumours at second-look resection were compared to basic patient and tumour characteristics. Results. There were 72 patients (56%) without and 57 with residual exophytic tumours. In the former group, 20 patients (28%) had carcinoma in situ, compared to 19 (33%) in the latter group. Potentially dangerous tumours (either carcinoma in situ, T1 or Ta grade 3) were observed in 55 patients (43%). Multiple tumours at primary resection were more prone to residual tumour at second-look resection than single tumours. No other tumour or patient characteristics could predict the occurrence of a residual tumour. Conclusions. Residual tumours are frequently observed at second-look resection 4-8 weeks after primary resection of T1 tumours. The majority of residual tumours detected at this stage are potentially dangerous; therefore, early second-look resection followed by intravesical instillation therapy is mandatory in patients with T1 tumours of the urinary bladder.}},
  author       = {{Jahnson, S and Wiklund, F and Duchek, M and Mestad, O and Rintala, E and Hellsten, Sverker and Malmstrom, PU}},
  issn         = {{0036-5599}},
  keywords     = {{bladder cancer; primary resection; second-look resection}},
  language     = {{eng}},
  number       = {{3}},
  pages        = {{206--210}},
  publisher    = {{Taylor & Francis}},
  series       = {{Scandinavian Journal of Urology and Nephrology}},
  title        = {{Results of second-look resection after primary resection of T1 tumour of the urinary bladder}},
  url          = {{http://dx.doi.org/10.1080/00365590510007793}},
  doi          = {{10.1080/00365590510007793}},
  volume       = {{39}},
  year         = {{2005}},
}