Cell-based therapy for Parkinson's disease : A journey through decades toward the light side of the Force
(2019) In European Journal of Neuroscience 49(4). p.463-471- Abstract
This review describes the history, development, and evolution of cell-based replacement therapy for Parkinson's disease (PD), from the first pioneering trials with fetal ventral midbrain progenitors to future trials using stem cells as well as reprogrammed cells. In the spirit of Tom Isaacs, the review takes parallels to the storyline of Star Wars, including the temptations from the dark side and the continuous fight for the light side of the Force. It is subdivided into headings based on the original movies, spanning from A New Hope to the Last Jedi.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8fdc8bc3-e4f1-4dc4-a332-b9676f65519a
- author
- Parmar, Malin LU ; Torper, Olof LU and Drouin-Ouellet, Janelle LU
- organization
- publishing date
- 2019
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- cell reprogramming, human embryonic stem cells, human-induced pluripotent stem cells, induced neurons, Parkinson's disease, Star Wars, transplantation
- in
- European Journal of Neuroscience
- volume
- 49
- issue
- 4
- pages
- 463 - 471
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:85053324584
- pmid:30099795
- ISSN
- 0953-816X
- DOI
- 10.1111/ejn.14109
- language
- English
- LU publication?
- yes
- id
- 8fdc8bc3-e4f1-4dc4-a332-b9676f65519a
- date added to LUP
- 2018-10-22 12:38:42
- date last changed
- 2024-07-08 21:54:11
@article{8fdc8bc3-e4f1-4dc4-a332-b9676f65519a, abstract = {{<p>This review describes the history, development, and evolution of cell-based replacement therapy for Parkinson's disease (PD), from the first pioneering trials with fetal ventral midbrain progenitors to future trials using stem cells as well as reprogrammed cells. In the spirit of Tom Isaacs, the review takes parallels to the storyline of Star Wars, including the temptations from the dark side and the continuous fight for the light side of the Force. It is subdivided into headings based on the original movies, spanning from A New Hope to the Last Jedi.</p>}}, author = {{Parmar, Malin and Torper, Olof and Drouin-Ouellet, Janelle}}, issn = {{0953-816X}}, keywords = {{cell reprogramming; human embryonic stem cells; human-induced pluripotent stem cells; induced neurons; Parkinson's disease; Star Wars; transplantation}}, language = {{eng}}, number = {{4}}, pages = {{463--471}}, publisher = {{Wiley-Blackwell}}, series = {{European Journal of Neuroscience}}, title = {{Cell-based therapy for Parkinson's disease : A journey through decades toward the light side of the Force}}, url = {{https://lup.lub.lu.se/search/files/100828413/Parmar_pdf_publication_in_eur_j_neurosci.pdf}}, doi = {{10.1111/ejn.14109}}, volume = {{49}}, year = {{2019}}, }