Frontotemporal dementia – Differentiation from Alzheimer's disease
(2004) In Psychogeriatria Polska 1(4). p.279-292- Abstract
- Organic dementia is dominated by primary degenerative disorders such as Alzheimer’s disease (AD) and frontotemporal dementia (FTD). FTD is a distinct clinical syndrome with behavioural, personality, emotional and language disturbances preceding the cognitive decline. This clinical presentation is distinctly different from that of AD which is characterized by early cognitive changes, such as memory impairment, aphasia and apraxia, and a relatively preserved personality and behaviour. The differences between these two conditions reflect the predominant topographic distribution of brain pathology.
The differences in clinical profiles and treatment strategies will be highlighted. In both disorders loss of functional ability,... (More) - Organic dementia is dominated by primary degenerative disorders such as Alzheimer’s disease (AD) and frontotemporal dementia (FTD). FTD is a distinct clinical syndrome with behavioural, personality, emotional and language disturbances preceding the cognitive decline. This clinical presentation is distinctly different from that of AD which is characterized by early cognitive changes, such as memory impairment, aphasia and apraxia, and a relatively preserved personality and behaviour. The differences between these two conditions reflect the predominant topographic distribution of brain pathology.
The differences in clinical profiles and treatment strategies will be highlighted. In both disorders loss of functional ability, development of behavioural disturbances and dependency impose heavy demands on family and other caregivers.
This presentation will concentrate on early recognition and diagnosis, using systematic clinical evaluation, neuropsychological testing and different brain imaging methods. This is important for a successful development of therapeutic strategies for both cognitive and behavioural symptoms in FTD and AD. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/955355
- author
- Gustafson, Lars LU ; Elfgren, Christina LU and Passant, Ulla LU
- organization
- publishing date
- 2004
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- neuropathology, neuroimaging, differential diagnosis, Alzheimer’s disease, frontotemporal dementia
- in
- Psychogeriatria Polska
- volume
- 1
- issue
- 4
- pages
- 279 - 292
- publisher
- Fundacja Ochrony Zdrowia Psychicznego
- ISSN
- 1732-2642
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Department of Psychogeriatrics (013304000)
- id
- 3d03c8b3-a312-4d5f-8add-770e76f98cb5 (old id 955355)
- date added to LUP
- 2016-04-01 15:25:36
- date last changed
- 2018-11-21 20:34:23
@article{3d03c8b3-a312-4d5f-8add-770e76f98cb5, abstract = {{Organic dementia is dominated by primary degenerative disorders such as Alzheimer’s disease (AD) and frontotemporal dementia (FTD). FTD is a distinct clinical syndrome with behavioural, personality, emotional and language disturbances preceding the cognitive decline. This clinical presentation is distinctly different from that of AD which is characterized by early cognitive changes, such as memory impairment, aphasia and apraxia, and a relatively preserved personality and behaviour. The differences between these two conditions reflect the predominant topographic distribution of brain pathology.<br/><br> The differences in clinical profiles and treatment strategies will be highlighted. In both disorders loss of functional ability, development of behavioural disturbances and dependency impose heavy demands on family and other caregivers.<br/><br> This presentation will concentrate on early recognition and diagnosis, using systematic clinical evaluation, neuropsychological testing and different brain imaging methods. This is important for a successful development of therapeutic strategies for both cognitive and behavioural symptoms in FTD and AD.}}, author = {{Gustafson, Lars and Elfgren, Christina and Passant, Ulla}}, issn = {{1732-2642}}, keywords = {{neuropathology; neuroimaging; differential diagnosis; Alzheimer’s disease; frontotemporal dementia}}, language = {{eng}}, number = {{4}}, pages = {{279--292}}, publisher = {{Fundacja Ochrony Zdrowia Psychicznego}}, series = {{Psychogeriatria Polska}}, title = {{Frontotemporal dementia – Differentiation from Alzheimer's disease}}, volume = {{1}}, year = {{2004}}, }