Alkanolamide biosurfactants: techno-economic evaluation of enzymatic versus chemical production
(2010) In Industrial Biotechnology 6(4). p.204-211- Abstract
- Alkanolamides are biosurfactants used in a range of products for cleaning and other applications. Recently, an environmentally benign and volume-efficient biocatalytic process for production of high-quality alkanolamides was developed in our laboratory. In the current investigation, this process is evaluated in terms of technical and economic feasibility on a multi-tonne scale using commercial process optimization software and compared with known chemical processes. Energy demands for the processes and in raw material production were also compared. A campaign for manufacturing 200 tonnes of alkanolamides was considered. When using a 20 m3 reactor and 5% (w/w) loading of an immobilized lipase (Novozym®435; Novozymes), 20 batches and a total... (More)
- Alkanolamides are biosurfactants used in a range of products for cleaning and other applications. Recently, an environmentally benign and volume-efficient biocatalytic process for production of high-quality alkanolamides was developed in our laboratory. In the current investigation, this process is evaluated in terms of technical and economic feasibility on a multi-tonne scale using commercial process optimization software and compared with known chemical processes. Energy demands for the processes and in raw material production were also compared. A campaign for manufacturing 200 tonnes of alkanolamides was considered. When using a 20 m3 reactor and 5% (w/w) loading of an immobilized lipase (Novozym®435; Novozymes), 20 batches and a total process time of 101 hours are required for the whole campaign. The biocatalytic process was relatively more energy-efficient, but production costs were calculated to be about 1.4 times that of the corresponding conventional alkanolamide manufacturing process utilizing sodium methylate as a catalyst. The principal contributor to the extra costs is the cost of the immobilized enzyme. There is a great potential to decrease enzyme costs; industrialization may, however, depend on the possibility of obtaining a higher price for the biocatalytic product. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/a6b7849d-825e-4be2-a840-0d3f45f194d4
- author
- Adlercreutz, Dietlind LU ; Tufvesson, Pär LU ; Karlsson, Annika J. and Hatti-Kaul, Rajni LU
- organization
- publishing date
- 2010
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Industrial Biotechnology
- volume
- 6
- issue
- 4
- pages
- 204 - 211
- publisher
- Mary Ann Liebert, Inc.
- external identifiers
-
- scopus:78650511575
- ISSN
- 1550-9087
- DOI
- 10.1089/ind.2010.6.204
- language
- English
- LU publication?
- yes
- id
- a6b7849d-825e-4be2-a840-0d3f45f194d4
- date added to LUP
- 2019-06-29 19:59:57
- date last changed
- 2022-01-31 22:55:36
@article{a6b7849d-825e-4be2-a840-0d3f45f194d4,
abstract = {{Alkanolamides are biosurfactants used in a range of products for cleaning and other applications. Recently, an environmentally benign and volume-efficient biocatalytic process for production of high-quality alkanolamides was developed in our laboratory. In the current investigation, this process is evaluated in terms of technical and economic feasibility on a multi-tonne scale using commercial process optimization software and compared with known chemical processes. Energy demands for the processes and in raw material production were also compared. A campaign for manufacturing 200 tonnes of alkanolamides was considered. When using a 20 m3 reactor and 5% (w/w) loading of an immobilized lipase (Novozym®435; Novozymes), 20 batches and a total process time of 101 hours are required for the whole campaign. The biocatalytic process was relatively more energy-efficient, but production costs were calculated to be about 1.4 times that of the corresponding conventional alkanolamide manufacturing process utilizing sodium methylate as a catalyst. The principal contributor to the extra costs is the cost of the immobilized enzyme. There is a great potential to decrease enzyme costs; industrialization may, however, depend on the possibility of obtaining a higher price for the biocatalytic product.}},
author = {{Adlercreutz, Dietlind and Tufvesson, Pär and Karlsson, Annika J. and Hatti-Kaul, Rajni}},
issn = {{1550-9087}},
language = {{eng}},
number = {{4}},
pages = {{204--211}},
publisher = {{Mary Ann Liebert, Inc.}},
series = {{Industrial Biotechnology}},
title = {{Alkanolamide biosurfactants: techno-economic evaluation of enzymatic versus chemical production}},
url = {{http://dx.doi.org/10.1089/ind.2010.6.204}},
doi = {{10.1089/ind.2010.6.204}},
volume = {{6}},
year = {{2010}},
}