Neuroendocrine differentiation in male breast carcinomas
(1992) In APMIS 100(7-12). p.720-726- Abstract
The presence of neuroendocrine differentiation, as expressed by cellular chromogranin immunoreactivity, was investigated in paraffin‐embedded tissue material from 51 consecutive cases of male breast carcinoma. From six of these cases electron microscopic studies were included. Chromogranin‐immunoreactive cells were present in solid cords and delineated tubular structures. Ultrastructurally, dense core secretory granules could be detected. The expression of neuroendocrine differentiation was 45%, which is between two and eight times higher than reported for female breast carcinomas by other investigators. The present findings suggest that male breast carcinoma is an exclusive tumour disease showing both similarities and discrepancies... (More)
The presence of neuroendocrine differentiation, as expressed by cellular chromogranin immunoreactivity, was investigated in paraffin‐embedded tissue material from 51 consecutive cases of male breast carcinoma. From six of these cases electron microscopic studies were included. Chromogranin‐immunoreactive cells were present in solid cords and delineated tubular structures. Ultrastructurally, dense core secretory granules could be detected. The expression of neuroendocrine differentiation was 45%, which is between two and eight times higher than reported for female breast carcinomas by other investigators. The present findings suggest that male breast carcinoma is an exclusive tumour disease showing both similarities and discrepancies when compared to its female counterpart.
(Less)
- author
- ALM, PER LU ; ALUMETS, JAN LU ; BAK‐JENSEN, ELISABET and OLSSON, HÅKAN LU
- organization
- publishing date
- 1992-01-01
- type
- Contribution to journal
- publication status
- published
- keywords
- Breast carcinoma, immunohistochemistry, neuroendocrine differentiation
- in
- APMIS
- volume
- 100
- issue
- 7-12
- pages
- 720 - 726
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- pmid:1325803
- scopus:0026782761
- ISSN
- 0903-4641
- DOI
- 10.1111/j.1699-0463.1992.tb03990.x
- language
- English
- LU publication?
- yes
- id
- c29b3703-04db-40ec-a148-a83a10d80af1
- date added to LUP
- 2018-12-19 15:48:32
- date last changed
- 2024-05-28 23:35:21
@article{c29b3703-04db-40ec-a148-a83a10d80af1, abstract = {{<p>The presence of neuroendocrine differentiation, as expressed by cellular chromogranin immunoreactivity, was investigated in paraffin‐embedded tissue material from 51 consecutive cases of male breast carcinoma. From six of these cases electron microscopic studies were included. Chromogranin‐immunoreactive cells were present in solid cords and delineated tubular structures. Ultrastructurally, dense core secretory granules could be detected. The expression of neuroendocrine differentiation was 45%, which is between two and eight times higher than reported for female breast carcinomas by other investigators. The present findings suggest that male breast carcinoma is an exclusive tumour disease showing both similarities and discrepancies when compared to its female counterpart.</p>}}, author = {{ALM, PER and ALUMETS, JAN and BAK‐JENSEN, ELISABET and OLSSON, HÅKAN}}, issn = {{0903-4641}}, keywords = {{Breast carcinoma; immunohistochemistry; neuroendocrine differentiation}}, language = {{eng}}, month = {{01}}, number = {{7-12}}, pages = {{720--726}}, publisher = {{John Wiley & Sons Inc.}}, series = {{APMIS}}, title = {{Neuroendocrine differentiation in male breast carcinomas}}, url = {{http://dx.doi.org/10.1111/j.1699-0463.1992.tb03990.x}}, doi = {{10.1111/j.1699-0463.1992.tb03990.x}}, volume = {{100}}, year = {{1992}}, }