Novel metabolites from the roots of Cadaba natalensis
(2016) In Phytochemistry Letters 16. p.283-286- Abstract
From an extract of the roots of Cadaba natalensis Sond. the novel macrocyclic dibenzo-diazacyclododecanedione 1 was isolated together with (S)-2-ethyl-2-methyloxazolidin-5-one (2a). In addition, the five known compounds were obtained. Of these, (R)-5-ethyl-5-methyloxazolidin-2-one (3) is reported as a natural product for the first time. The structures of the isolated compounds were elucidated by analysis of the spectral data, 1D NMR (1H, 13C, and DEPT), 2D NMR (COSY, HMQC, HMBC, and NOESY), and HRESIMS, as well as by the comparison with previously reported data.
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- author
- Monjane, J. A. LU ; Uamusse, A. and Sterner, O. LU
- organization
- publishing date
- 2016-06-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Cadaba natalensis, Diazacyclododecanedione, Isolation, Isoquiniline alkaloids, Oxazolidinone, Structure elucidation
- in
- Phytochemistry Letters
- volume
- 16
- pages
- 4 pages
- publisher
- Elsevier
- external identifiers
-
- wos:000378027300050
- scopus:84977613805
- ISSN
- 1874-3900
- DOI
- 10.1016/j.phytol.2016.05.009
- language
- English
- LU publication?
- yes
- id
- daece9fb-3486-426a-8d97-233f79da4ffb
- date added to LUP
- 2017-01-25 13:40:04
- date last changed
- 2024-06-29 00:08:23
@article{daece9fb-3486-426a-8d97-233f79da4ffb, abstract = {{<p>From an extract of the roots of Cadaba natalensis Sond. the novel macrocyclic dibenzo-diazacyclododecanedione 1 was isolated together with (S)-2-ethyl-2-methyloxazolidin-5-one (2a). In addition, the five known compounds were obtained. Of these, (R)-5-ethyl-5-methyloxazolidin-2-one (3) is reported as a natural product for the first time. The structures of the isolated compounds were elucidated by analysis of the spectral data, 1D NMR (<sup>1</sup>H, <sup>13</sup>C, and DEPT), 2D NMR (COSY, HMQC, HMBC, and NOESY), and HRESIMS, as well as by the comparison with previously reported data.</p>}}, author = {{Monjane, J. A. and Uamusse, A. and Sterner, O.}}, issn = {{1874-3900}}, keywords = {{Cadaba natalensis; Diazacyclododecanedione; Isolation; Isoquiniline alkaloids; Oxazolidinone; Structure elucidation}}, language = {{eng}}, month = {{06}}, pages = {{283--286}}, publisher = {{Elsevier}}, series = {{Phytochemistry Letters}}, title = {{Novel metabolites from the roots of Cadaba natalensis}}, url = {{http://dx.doi.org/10.1016/j.phytol.2016.05.009}}, doi = {{10.1016/j.phytol.2016.05.009}}, volume = {{16}}, year = {{2016}}, }