Associations between Divorce and Onset of Drug Abuse in a Swedish National Sample
(2018) In American Journal of Epidemiology 187(5). p.1010-1018- Abstract
Rates of drug abuse are higher among divorced individuals than among those who are married, but it is not clear whether divorce itself is a risk factor for drug abuse or whether the observed association is confounded by other factors. We examined the association between divorce and onset of drug abuse in a population-based Swedish cohort born during 1965-1975 (n = 651,092) using Cox proportional hazards methods, with marital status as a time-varying covariate. Potential confounders (e.g., demographics, adolescent deviance, and family history of drug abuse) were included as covariates. Parallel analyses were conducted for widowhood and drug-Abuse onset. In models with adjustments, divorce was associated with a substantial increase in... (More)
Rates of drug abuse are higher among divorced individuals than among those who are married, but it is not clear whether divorce itself is a risk factor for drug abuse or whether the observed association is confounded by other factors. We examined the association between divorce and onset of drug abuse in a population-based Swedish cohort born during 1965-1975 (n = 651,092) using Cox proportional hazards methods, with marital status as a time-varying covariate. Potential confounders (e.g., demographics, adolescent deviance, and family history of drug abuse) were included as covariates. Parallel analyses were conducted for widowhood and drug-Abuse onset. In models with adjustments, divorce was associated with a substantial increase in risk of drug-Abuse onset in both sexes (hazard ratios > 5). Co-relative analyses (among biological relatives) were consistent with a partially causal role of divorce on drug-Abuse onset. Widowhood also increased risk of drug-Abuse onset, although to a lesser extent. Divorce is a potent risk factor for onset of drug abuse, even after adjusting for deviant behavior in adolescence and family history of drug abuse. The somewhat less-pronounced association with widowhood, particularly among men, suggests that the magnitude of association between divorce and drug abuse may not be generalizable to the end of a relationship.
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- author
- Edwards, Alexis C. ; Larsson Lönn, Sara LU ; Sundquist, Jan LU ; Kendler, Kenneth S. and Sundquist, Kristina LU
- organization
- publishing date
- 2018-05-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- addiction, divorce, drug abuse, family history, widowhood
- in
- American Journal of Epidemiology
- volume
- 187
- issue
- 5
- pages
- 9 pages
- publisher
- Oxford University Press
- external identifiers
-
- pmid:29155917
- scopus:85047130147
- ISSN
- 0002-9262
- DOI
- 10.1093/aje/kwx321
- language
- English
- LU publication?
- yes
- id
- e0377490-f3b5-41c7-ba89-2f12a892871d
- date added to LUP
- 2018-10-29 09:31:40
- date last changed
- 2024-09-18 05:25:20
@article{e0377490-f3b5-41c7-ba89-2f12a892871d, abstract = {{<p>Rates of drug abuse are higher among divorced individuals than among those who are married, but it is not clear whether divorce itself is a risk factor for drug abuse or whether the observed association is confounded by other factors. We examined the association between divorce and onset of drug abuse in a population-based Swedish cohort born during 1965-1975 (n = 651,092) using Cox proportional hazards methods, with marital status as a time-varying covariate. Potential confounders (e.g., demographics, adolescent deviance, and family history of drug abuse) were included as covariates. Parallel analyses were conducted for widowhood and drug-Abuse onset. In models with adjustments, divorce was associated with a substantial increase in risk of drug-Abuse onset in both sexes (hazard ratios > 5). Co-relative analyses (among biological relatives) were consistent with a partially causal role of divorce on drug-Abuse onset. Widowhood also increased risk of drug-Abuse onset, although to a lesser extent. Divorce is a potent risk factor for onset of drug abuse, even after adjusting for deviant behavior in adolescence and family history of drug abuse. The somewhat less-pronounced association with widowhood, particularly among men, suggests that the magnitude of association between divorce and drug abuse may not be generalizable to the end of a relationship.</p>}}, author = {{Edwards, Alexis C. and Larsson Lönn, Sara and Sundquist, Jan and Kendler, Kenneth S. and Sundquist, Kristina}}, issn = {{0002-9262}}, keywords = {{addiction; divorce; drug abuse; family history; widowhood}}, language = {{eng}}, month = {{05}}, number = {{5}}, pages = {{1010--1018}}, publisher = {{Oxford University Press}}, series = {{American Journal of Epidemiology}}, title = {{Associations between Divorce and Onset of Drug Abuse in a Swedish National Sample}}, url = {{http://dx.doi.org/10.1093/aje/kwx321}}, doi = {{10.1093/aje/kwx321}}, volume = {{187}}, year = {{2018}}, }