Immunsvar och inflammation vid Crohns sjukdom. Snart möjligt driva diagnostiken längre och utveckla mer specifika läkemedel
(1999) In Läkartidningen 96(1-2). p.5-52- Abstract
The chronic inflammation in Crohn's disease may be caused by aggressive response to bacterial antigens normal to the gut. Genetic and environmental factors modify the inflammatory response evoked by damage to the mucosal gut barrier. Genetic factors may also determine the subsequent course of chronic inflammation. Further elucidation of the pathogenesis might improve our understanding of the heterogenous nature of Crohn's disease, thus enabling the disease to be subtyped and individualised therapy directed primarily at down-regulation of helper T-cell-1 response to be developed.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/e057fac2-e27a-421e-be4b-5ffcfb026680
- author
- Lindgren, S LU and Egesten, A LU
- alternative title
- Immune response and inflammation in Crohn disease. More detailed diagnostics and more specific drugs are soon to be available
- publishing date
- 1999-01-06
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Crohn Disease, Humans, T-Lymphocytes, Helper-Inducer, English Abstract, Journal Article, Review
- in
- Läkartidningen
- volume
- 96
- issue
- 1-2
- pages
- 4 pages
- publisher
- Swedish Medical Association
- external identifiers
-
- pmid:9951251
- ISSN
- 0023-7205
- language
- Swedish
- LU publication?
- no
- id
- e057fac2-e27a-421e-be4b-5ffcfb026680
- date added to LUP
- 2017-02-03 16:07:12
- date last changed
- 2021-07-31 04:01:04
@article{e057fac2-e27a-421e-be4b-5ffcfb026680, abstract = {{<p>The chronic inflammation in Crohn's disease may be caused by aggressive response to bacterial antigens normal to the gut. Genetic and environmental factors modify the inflammatory response evoked by damage to the mucosal gut barrier. Genetic factors may also determine the subsequent course of chronic inflammation. Further elucidation of the pathogenesis might improve our understanding of the heterogenous nature of Crohn's disease, thus enabling the disease to be subtyped and individualised therapy directed primarily at down-regulation of helper T-cell-1 response to be developed.</p>}}, author = {{Lindgren, S and Egesten, A}}, issn = {{0023-7205}}, keywords = {{Crohn Disease; Humans; T-Lymphocytes, Helper-Inducer; English Abstract; Journal Article; Review}}, language = {{swe}}, month = {{01}}, number = {{1-2}}, pages = {{5--52}}, publisher = {{Swedish Medical Association}}, series = {{Läkartidningen}}, title = {{Immunsvar och inflammation vid Crohns sjukdom. Snart möjligt driva diagnostiken längre och utveckla mer specifika läkemedel}}, volume = {{96}}, year = {{1999}}, }