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Subclinical hypothyroidism presenting with gait abnormality.

Edvardsson, Bengt LU and Persson, Staffan LU (2010) In The Neurologist 16(2). p.115-116
Abstract
Subclinical thyroid disease is a common disorder, particularly in middle-aged and elderly individuals. Some patients with manifest hypothyroidism complain of unsteadiness of gait. The management of subclinical hypothyroidism is controversial. A 61-year-old man presented with a mild gait abnormality. He walked unsteadily on a broad base. Examination revealed a slight cerebellar ataxic gait. Laboratory evaluation showed elevated levels of thyroid-stimulating hormone. Serum free thyroxine was normal and thyroglobulin antibodies were present. Computer tomography of the patient's head was normal, as were other investigations. The patient responded rapidly to thyroxin treatment with resolution of the gait disturbance. A laboratory evaluation of... (More)
Subclinical thyroid disease is a common disorder, particularly in middle-aged and elderly individuals. Some patients with manifest hypothyroidism complain of unsteadiness of gait. The management of subclinical hypothyroidism is controversial. A 61-year-old man presented with a mild gait abnormality. He walked unsteadily on a broad base. Examination revealed a slight cerebellar ataxic gait. Laboratory evaluation showed elevated levels of thyroid-stimulating hormone. Serum free thyroxine was normal and thyroglobulin antibodies were present. Computer tomography of the patient's head was normal, as were other investigations. The patient responded rapidly to thyroxin treatment with resolution of the gait disturbance. A laboratory evaluation of thyroid function should be performed in similar cases, and treatment should be initiated when called for. Subclinical hypothyroidism can present as a cerebellar ataxic gait. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
The Neurologist
volume
16
issue
2
pages
115 - 116
publisher
Lippincott Williams & Wilkins
external identifiers
  • WOS:000275490500008
  • PMID:20220447
  • Scopus:77949458792
ISSN
1074-7931
DOI
10.1097/NRL.0b013e3181be6fdb
language
English
LU publication?
yes
id
3f0964b6-fe6b-4896-a9e9-35bc54322281 (old id 1582324)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/20220447?dopt=Abstract
date added to LUP
2010-04-07 16:10:04
date last changed
2016-10-13 04:26:14
@misc{3f0964b6-fe6b-4896-a9e9-35bc54322281,
  abstract     = {Subclinical thyroid disease is a common disorder, particularly in middle-aged and elderly individuals. Some patients with manifest hypothyroidism complain of unsteadiness of gait. The management of subclinical hypothyroidism is controversial. A 61-year-old man presented with a mild gait abnormality. He walked unsteadily on a broad base. Examination revealed a slight cerebellar ataxic gait. Laboratory evaluation showed elevated levels of thyroid-stimulating hormone. Serum free thyroxine was normal and thyroglobulin antibodies were present. Computer tomography of the patient's head was normal, as were other investigations. The patient responded rapidly to thyroxin treatment with resolution of the gait disturbance. A laboratory evaluation of thyroid function should be performed in similar cases, and treatment should be initiated when called for. Subclinical hypothyroidism can present as a cerebellar ataxic gait.},
  author       = {Edvardsson, Bengt and Persson, Staffan},
  issn         = {1074-7931},
  language     = {eng},
  number       = {2},
  pages        = {115--116},
  publisher    = {ARRAY(0x9b8f530)},
  series       = {The Neurologist},
  title        = {Subclinical hypothyroidism presenting with gait abnormality.},
  url          = {http://dx.doi.org/10.1097/NRL.0b013e3181be6fdb},
  volume       = {16},
  year         = {2010},
}