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Reduction of flow velocities in patients with ischemic events in the middle cerebral artery--long-term follow-up with ultrasound.

Kremer, Christine LU and Abul-Kasim, Kasim LU (2011) In Acta Neurologica Belgica 111(2). p.111-115
Abstract
Data concerning the persistent reduction of flow velocities measured by transcranial color-coded sonography (TCCS) in relation to the clinical and radiological outcome among patients with ischemic events in middle cerebral artery (MCA) territory is scarce. Patients with > or = 50% reduction of peak systolic velocities (PSV-MCA) as compared to the contralateral MCA were prospectively included in follow-up by TCCS (mean 404 days). Out of 849 patients with stroke admitted to our stroke unit, 25 patients showed reduced PSV-MCA and included in the analyses of this study. Ten (40%) survivors showed persistent reduction of PSV-MCA. None of the patients with normalized PSV-MCA suffered an ischemic event compared with three patients with... (More)
Data concerning the persistent reduction of flow velocities measured by transcranial color-coded sonography (TCCS) in relation to the clinical and radiological outcome among patients with ischemic events in middle cerebral artery (MCA) territory is scarce. Patients with > or = 50% reduction of peak systolic velocities (PSV-MCA) as compared to the contralateral MCA were prospectively included in follow-up by TCCS (mean 404 days). Out of 849 patients with stroke admitted to our stroke unit, 25 patients showed reduced PSV-MCA and included in the analyses of this study. Ten (40%) survivors showed persistent reduction of PSV-MCA. None of the patients with normalized PSV-MCA suffered an ischemic event compared with three patients with persistent reduction of PSV-MCA (all had ipsilateral occlusion of the internal carotid artery caused by dissection). Patients with persistently reduced PSV-MCA exhibited significantly (Mann-Whitney test, p = 0.02) larger infarct volumes on CT (mean +/- SD 38 +/-50 cm3) compared to those with normalized PSV-MCA (6 +/- 7 cm3). The functional outcome were, however, similar in patients with normalized and those with persistently reduced PSV-MCA. We found that a relatively high percentage (40%) of patients suffered ischemic event in the MCA territory with initial reduction of flow velocity on TCCS showed persistent reduction on long term follow-up. (Less)
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Neurologica Belgica
volume
111
issue
2
pages
111 - 115
publisher
Springer
external identifiers
  • wos:000292524600005
  • pmid:21748929
  • scopus:79959462212
ISSN
2240-2993
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Neurology, Malmö (013027010), Medical Radiology Unit (013241410)
id
15e0e86e-05c8-412f-9768-c771c6f1595c (old id 2058726)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/21748929?dopt=Abstract
date added to LUP
2016-04-04 09:32:35
date last changed
2022-01-29 18:21:45
@article{15e0e86e-05c8-412f-9768-c771c6f1595c,
  abstract     = {{Data concerning the persistent reduction of flow velocities measured by transcranial color-coded sonography (TCCS) in relation to the clinical and radiological outcome among patients with ischemic events in middle cerebral artery (MCA) territory is scarce. Patients with > or = 50% reduction of peak systolic velocities (PSV-MCA) as compared to the contralateral MCA were prospectively included in follow-up by TCCS (mean 404 days). Out of 849 patients with stroke admitted to our stroke unit, 25 patients showed reduced PSV-MCA and included in the analyses of this study. Ten (40%) survivors showed persistent reduction of PSV-MCA. None of the patients with normalized PSV-MCA suffered an ischemic event compared with three patients with persistent reduction of PSV-MCA (all had ipsilateral occlusion of the internal carotid artery caused by dissection). Patients with persistently reduced PSV-MCA exhibited significantly (Mann-Whitney test, p = 0.02) larger infarct volumes on CT (mean +/- SD 38 +/-50 cm3) compared to those with normalized PSV-MCA (6 +/- 7 cm3). The functional outcome were, however, similar in patients with normalized and those with persistently reduced PSV-MCA. We found that a relatively high percentage (40%) of patients suffered ischemic event in the MCA territory with initial reduction of flow velocity on TCCS showed persistent reduction on long term follow-up.}},
  author       = {{Kremer, Christine and Abul-Kasim, Kasim}},
  issn         = {{2240-2993}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{111--115}},
  publisher    = {{Springer}},
  series       = {{Acta Neurologica Belgica}},
  title        = {{Reduction of flow velocities in patients with ischemic events in the middle cerebral artery--long-term follow-up with ultrasound.}},
  url          = {{http://www.ncbi.nlm.nih.gov/pubmed/21748929?dopt=Abstract}},
  volume       = {{111}},
  year         = {{2011}},
}