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Cartilage mechanics and morphology, synovitis and proteoglycan fragments in rabbit joint fluid after prosthetic meniscal substitution

Messner, Karola; Lohmander, L. Stefan LU and Gillquist, Jan (1993) In Biomaterials 14(3). p.163-168
Abstract

The effects of meniscal substitution with a Dacron® or Teflon® prosthesis on rabbit knee-joint cartilage were studied by indentation tests, gross and histological inspection, analysis of proteoglycan fragments in joint fluid and an evaluation of synovial changes. Cartilage mechanics and cartilage morphology were similarly abnormal after meniscectomy and meniscal substitution. The elevated concentrations of proteoglycan fragments in joint fluid and the more severe synovial changes in joints with a meniscal substitute, as compared to meniscectomy, probably resulted from irritation of the artificial implant, but also reflected the remaining effects from the necessary bone drilling. In this short-term experiment, the use of an artificial... (More)

The effects of meniscal substitution with a Dacron® or Teflon® prosthesis on rabbit knee-joint cartilage were studied by indentation tests, gross and histological inspection, analysis of proteoglycan fragments in joint fluid and an evaluation of synovial changes. Cartilage mechanics and cartilage morphology were similarly abnormal after meniscectomy and meniscal substitution. The elevated concentrations of proteoglycan fragments in joint fluid and the more severe synovial changes in joints with a meniscal substitute, as compared to meniscectomy, probably resulted from irritation of the artificial implant, but also reflected the remaining effects from the necessary bone drilling. In this short-term experiment, the use of an artificial meniscal substitute could not prevent cartilage degeneration after meniscectomy. © 1993.

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Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Dacron®, Knee-joint prosthesis, meniscectomy, proteoglycan, synovitis, Teflon®
in
Biomaterials
volume
14
issue
3
pages
6 pages
publisher
Elsevier
external identifiers
  • Scopus:0027551632
ISSN
0142-9612
DOI
10.1016/0142-9612(93)90018-W
language
English
LU publication?
yes
id
21dac920-10b7-45cd-86d9-266c433489c5
date added to LUP
2016-05-04 18:31:22
date last changed
2016-05-26 13:12:53
@misc{21dac920-10b7-45cd-86d9-266c433489c5,
  abstract     = {<p>The effects of meniscal substitution with a Dacron® or Teflon® prosthesis on rabbit knee-joint cartilage were studied by indentation tests, gross and histological inspection, analysis of proteoglycan fragments in joint fluid and an evaluation of synovial changes. Cartilage mechanics and cartilage morphology were similarly abnormal after meniscectomy and meniscal substitution. The elevated concentrations of proteoglycan fragments in joint fluid and the more severe synovial changes in joints with a meniscal substitute, as compared to meniscectomy, probably resulted from irritation of the artificial implant, but also reflected the remaining effects from the necessary bone drilling. In this short-term experiment, the use of an artificial meniscal substitute could not prevent cartilage degeneration after meniscectomy. © 1993.</p>},
  author       = {Messner, Karola and Lohmander, L. Stefan and Gillquist, Jan},
  issn         = {0142-9612},
  keyword      = {Dacron®,Knee-joint prosthesis,meniscectomy,proteoglycan,synovitis,Teflon®},
  language     = {eng},
  number       = {3},
  pages        = {163--168},
  publisher    = {ARRAY(0xb566168)},
  series       = {Biomaterials},
  title        = {Cartilage mechanics and morphology, synovitis and proteoglycan fragments in rabbit joint fluid after prosthetic meniscal substitution},
  url          = {http://dx.doi.org/10.1016/0142-9612(93)90018-W},
  volume       = {14},
  year         = {1993},
}