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Risk of cutaneous malignant melanoma in relation to use of sunbeds : further evidence for UV-A carcinogenicity

Westerdahl, J LU ; Ingvar, C LU ; Måsbäck, A LU ; Jonsson, N and Olsson, Håkan LU (2000) In British Journal of Cancer 82(9). p.1593-1599
Abstract

In a population-based, matched, case-control study from southern Sweden of 571 patients with a first diagnosis of cutaneous malignant melanoma and 913 healthy controls aged 16-80 years, the association between sunbed use and malignant melanoma was evaluated. A total of 250 (44%) cases and 372 (41%) controls reported ever having used sunbeds. A significantly elevated odds ratio for developing malignant melanoma after regular exposure to sunbeds was found, adjusted for hair colour, raised naevi, skin type and number of sunburns (odds ratio (OR) 1.8, 95% confidence interval (CI) 1.2-2.7). A dose-response relationship between total number of sunbed uses and melanoma risk was only found up to the level of 250 times. The OR was higher in... (More)

In a population-based, matched, case-control study from southern Sweden of 571 patients with a first diagnosis of cutaneous malignant melanoma and 913 healthy controls aged 16-80 years, the association between sunbed use and malignant melanoma was evaluated. A total of 250 (44%) cases and 372 (41%) controls reported ever having used sunbeds. A significantly elevated odds ratio for developing malignant melanoma after regular exposure to sunbeds was found, adjusted for hair colour, raised naevi, skin type and number of sunburns (odds ratio (OR) 1.8, 95% confidence interval (CI) 1.2-2.7). A dose-response relationship between total number of sunbed uses and melanoma risk was only found up to the level of 250 times. The OR was higher in individuals younger than age 36 years (adjusted OR 8.1, 95% CI 1.3-49.5 for regular vs. never use). The association seemed to be true only for subjects with black/dark brown or light brown hair and among females. Lesions of the extremities showed the strongest association of increased risk with sunbed use. An increased risk was related to commercial exposure and to exposure during the winter. The results substantiate the hypothesis that exposure to sunbeds might increase the risk of developing malignant melanoma.

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Contribution to journal
publication status
published
subject
keywords
Adolescent, Adult, Aged, Aged, 80 and over, Confidence Intervals, Female, Heliotherapy, Humans, Male, Melanoma, Middle Aged, Neoplasms, Radiation-Induced, Odds Ratio, Skin Neoplasms, Surveys and Questionnaires, Ultraviolet Rays
in
British Journal of Cancer
volume
82
issue
9
pages
1593 - 1599
publisher
Nature Publishing Group
external identifiers
  • Scopus:0034115308
ISSN
0007-0920
DOI
10.1054/bjoc.1999.1181
language
English
LU publication?
yes
id
3a49c09f-8a33-4232-b06d-4192db820896
date added to LUP
2016-09-18 12:29:28
date last changed
2016-10-13 05:13:42
@misc{3a49c09f-8a33-4232-b06d-4192db820896,
  abstract     = {<p>In a population-based, matched, case-control study from southern Sweden of 571 patients with a first diagnosis of cutaneous malignant melanoma and 913 healthy controls aged 16-80 years, the association between sunbed use and malignant melanoma was evaluated. A total of 250 (44%) cases and 372 (41%) controls reported ever having used sunbeds. A significantly elevated odds ratio for developing malignant melanoma after regular exposure to sunbeds was found, adjusted for hair colour, raised naevi, skin type and number of sunburns (odds ratio (OR) 1.8, 95% confidence interval (CI) 1.2-2.7). A dose-response relationship between total number of sunbed uses and melanoma risk was only found up to the level of 250 times. The OR was higher in individuals younger than age 36 years (adjusted OR 8.1, 95% CI 1.3-49.5 for regular vs. never use). The association seemed to be true only for subjects with black/dark brown or light brown hair and among females. Lesions of the extremities showed the strongest association of increased risk with sunbed use. An increased risk was related to commercial exposure and to exposure during the winter. The results substantiate the hypothesis that exposure to sunbeds might increase the risk of developing malignant melanoma.</p>},
  author       = {Westerdahl, J and Ingvar, C and Måsbäck, A and Jonsson, N and Olsson, Håkan},
  issn         = {0007-0920},
  keyword      = {Adolescent,Adult,Aged,Aged, 80 and over,Confidence Intervals,Female,Heliotherapy,Humans,Male,Melanoma,Middle Aged,Neoplasms, Radiation-Induced,Odds Ratio,Skin Neoplasms,Surveys and Questionnaires,Ultraviolet Rays},
  language     = {eng},
  number       = {9},
  pages        = {1593--1599},
  publisher    = {ARRAY(0xab5e9f8)},
  series       = {British Journal of Cancer},
  title        = {Risk of cutaneous malignant melanoma in relation to use of sunbeds : further evidence for UV-A carcinogenicity},
  url          = {http://dx.doi.org/10.1054/bjoc.1999.1181},
  volume       = {82},
  year         = {2000},
}