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Evolutionary relations between subtypes of telomere-associated repeats in Chironomus

Cohn, Marita LU and Edström, Jan-Erik LU (1991) In Journal of Molecular Evolution 32(6). p.463-468
Abstract
Telomere-associated DNA in Chironomus pallidivittatus contains tandemly repeated 340-bp units. We show that they are distributed among several subtypes of which we have characterized two, M1 and D1, with regard to base sequence, homogeneity, and intertelomeric distribution. Each subpopulation is highly homogeneous and the two subtypes have identical consensus sequences throughout 90% of their lengths. In the remaining part the homology is only about 60%. Each subpopulation has its specific intertelomeric distribution and there is no difference in the degree of homogenization within and between telomeres. The repeat unit contains two pairs of subrepeats embedded in linker DNA. This provides a model that makes it possible to relate the two... (More)
Telomere-associated DNA in Chironomus pallidivittatus contains tandemly repeated 340-bp units. We show that they are distributed among several subtypes of which we have characterized two, M1 and D1, with regard to base sequence, homogeneity, and intertelomeric distribution. Each subpopulation is highly homogeneous and the two subtypes have identical consensus sequences throughout 90% of their lengths. In the remaining part the homology is only about 60%. Each subpopulation has its specific intertelomeric distribution and there is no difference in the degree of homogenization within and between telomeres. The repeat unit contains two pairs of subrepeats embedded in linker DNA. This provides a model that makes it possible to relate the two subtypes to each other with regard to evolutionary history. The difference between the two subtypes is due to mutations that have occurred in only one of them, D1, resulting in a decreased similarity between one of its pairs of subrepeats. This type of repeat unit is therefore believed to be derived from the other, M1. The local decrease in similarity between M1 and D1 suggests that homogenization between them occurs by gene conversion. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Molecular Evolution
volume
32
issue
6
pages
463 - 468
publisher
Springer
external identifiers
  • Scopus:0025881010
ISSN
0022-2844
DOI
10.1007/BF02102648
language
English
LU publication?
yes
id
98a4532c-f725-4c48-8f86-41d02f32801d (old id 4739979)
date added to LUP
2014-11-06 11:36:56
date last changed
2016-10-13 04:42:56
@misc{98a4532c-f725-4c48-8f86-41d02f32801d,
  abstract     = {Telomere-associated DNA in Chironomus pallidivittatus contains tandemly repeated 340-bp units. We show that they are distributed among several subtypes of which we have characterized two, M1 and D1, with regard to base sequence, homogeneity, and intertelomeric distribution. Each subpopulation is highly homogeneous and the two subtypes have identical consensus sequences throughout 90% of their lengths. In the remaining part the homology is only about 60%. Each subpopulation has its specific intertelomeric distribution and there is no difference in the degree of homogenization within and between telomeres. The repeat unit contains two pairs of subrepeats embedded in linker DNA. This provides a model that makes it possible to relate the two subtypes to each other with regard to evolutionary history. The difference between the two subtypes is due to mutations that have occurred in only one of them, D1, resulting in a decreased similarity between one of its pairs of subrepeats. This type of repeat unit is therefore believed to be derived from the other, M1. The local decrease in similarity between M1 and D1 suggests that homogenization between them occurs by gene conversion.},
  author       = {Cohn, Marita and Edström, Jan-Erik},
  issn         = {0022-2844},
  language     = {eng},
  number       = {6},
  pages        = {463--468},
  publisher    = {ARRAY(0x8ef06f8)},
  series       = {Journal of Molecular Evolution},
  title        = {Evolutionary relations between subtypes of telomere-associated repeats in Chironomus},
  url          = {http://dx.doi.org/10.1007/BF02102648},
  volume       = {32},
  year         = {1991},
}