Factors limiting physical working capacity in predialytic uraemic patients
(1987) In Acta Medica Scandinavica 222(2). p.183-190- Abstract
The exercise capacity of 20 predialytic uraemic patients (mean age 43 ± 12 years) was studied prospectively. Nine of these patients were examined twice in a longitudinal study. The maximal working capacity, measured by standardized exercise test on a bicycle ergometer, averaged 74 ± 19% of the expected normal. Normal exercise ECG were registered in 16 out of 20 patients. Total hemoglobin/kg body weight (THb) was 67 ± 16% of the expected normal and serum parathyroid hormone concentration (PTH) was 39 ± 39 μg/l (normal range 0.5-1.5). Partial correlation showed a correlation between exercise capacity and PTH (p <0.05). In the longitudinal study the decrease in steady state exercise capacity was correlated to the decrease in THb (p... (More)
The exercise capacity of 20 predialytic uraemic patients (mean age 43 ± 12 years) was studied prospectively. Nine of these patients were examined twice in a longitudinal study. The maximal working capacity, measured by standardized exercise test on a bicycle ergometer, averaged 74 ± 19% of the expected normal. Normal exercise ECG were registered in 16 out of 20 patients. Total hemoglobin/kg body weight (THb) was 67 ± 16% of the expected normal and serum parathyroid hormone concentration (PTH) was 39 ± 39 μg/l (normal range 0.5-1.5). Partial correlation showed a correlation between exercise capacity and PTH (p <0.05). In the longitudinal study the decrease in steady state exercise capacity was correlated to the decrease in THb (p <0.05), but not to the increase in PTH. In conclusion, patients with predialytic uraemia have a reduced maximal working capacity, due to several possible factors one of which is a reduced THb. Ischaemic heart disease seems to be of minor importance.
(Less)
- author
- Clyne, N. LU ; Jogestrand, T. ; Lins, L. E. ; Pehrsson, S. K. and Ekelund, L. G.
- publishing date
- 1987
- type
- Contribution to journal
- publication status
- published
- in
- Acta Medica Scandinavica
- volume
- 222
- issue
- 2
- pages
- 8 pages
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:0023183584
- pmid:3673671
- ISSN
- 0001-6101
- language
- English
- LU publication?
- no
- id
- 4d5104ac-f3ea-4b70-b1a3-a832c0157665
- date added to LUP
- 2016-08-30 22:10:31
- date last changed
- 2024-01-19 08:10:07
@article{4d5104ac-f3ea-4b70-b1a3-a832c0157665, abstract = {{<p>The exercise capacity of 20 predialytic uraemic patients (mean age 43 ± 12 years) was studied prospectively. Nine of these patients were examined twice in a longitudinal study. The maximal working capacity, measured by standardized exercise test on a bicycle ergometer, averaged 74 ± 19% of the expected normal. Normal exercise ECG were registered in 16 out of 20 patients. Total hemoglobin/kg body weight (THb) was 67 ± 16% of the expected normal and serum parathyroid hormone concentration (PTH) was 39 ± 39 μg/l (normal range 0.5-1.5). Partial correlation showed a correlation between exercise capacity and PTH (p <0.05). In the longitudinal study the decrease in steady state exercise capacity was correlated to the decrease in THb (p <0.05), but not to the increase in PTH. In conclusion, patients with predialytic uraemia have a reduced maximal working capacity, due to several possible factors one of which is a reduced THb. Ischaemic heart disease seems to be of minor importance.</p>}}, author = {{Clyne, N. and Jogestrand, T. and Lins, L. E. and Pehrsson, S. K. and Ekelund, L. G.}}, issn = {{0001-6101}}, language = {{eng}}, number = {{2}}, pages = {{183--190}}, publisher = {{Wiley-Blackwell}}, series = {{Acta Medica Scandinavica}}, title = {{Factors limiting physical working capacity in predialytic uraemic patients}}, volume = {{222}}, year = {{1987}}, }