Increased integrity of white matter pathways after dual n-back training
(2016) In NeuroImage 133. p.244-250- Abstract
Dual n-back WM training has been shown to produce broad transfer effects to different untrained cognitive functions. The task is demanding to the cognitive system because it includes a bi-modal (auditory and visual) dual-task component. A previous WM training study showed increased white matter integrity in the parietal lobe as well as the anterior part of the corpus callosum after visual n-back training. We investigated dual n-back training-related changes in white matter pathways. We anticipated dual n-back training to increase white matter integrity in pathways that connect brain regions related to WM processes. Additionally, we hypothesized that dual n-back training would produce more brain-wide white matter changes than single... (More)
Dual n-back WM training has been shown to produce broad transfer effects to different untrained cognitive functions. The task is demanding to the cognitive system because it includes a bi-modal (auditory and visual) dual-task component. A previous WM training study showed increased white matter integrity in the parietal lobe as well as the anterior part of the corpus callosum after visual n-back training. We investigated dual n-back training-related changes in white matter pathways. We anticipated dual n-back training to increase white matter integrity in pathways that connect brain regions related to WM processes. Additionally, we hypothesized that dual n-back training would produce more brain-wide white matter changes than single n-back training because of the involvement of two modalities and the additional dual-task coordination component of the task. The dual n-back training group showed increased white matter integrity (reflected as increased fractional anisotropy, FA) after training. The effects were mostly left lateralized as compared with changes from pretest to posttest in the passive and active control groups. Additionally, significant effects were observed in the anterior part of the corpus callosum, when the training group was compared with the passive control group. There were no changes in pretest to posttest FA changes between the passive and active control groups. The results therefore show that dual n-back training produces increased integrity in white matter pathways connecting different brain regions. The results are discussed in reference to the bi-modal dual-task component of the training task.
(Less)
- author
- Salminen, Tiina ; Mårtensson, Johan LU ; Schubert, Torsten and Kühn, Simone
- organization
- publishing date
- 2016-06-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Plasticity, White matter, Working memory training
- in
- NeuroImage
- volume
- 133
- pages
- 7 pages
- publisher
- Elsevier
- external identifiers
-
- pmid:27001498
- wos:000377048600021
- scopus:84962032927
- ISSN
- 1053-8119
- DOI
- 10.1016/j.neuroimage.2016.03.028
- language
- English
- LU publication?
- yes
- id
- 5451b230-1660-4838-a363-458298368c0d
- date added to LUP
- 2016-04-27 16:24:07
- date last changed
- 2024-04-04 18:01:28
@article{5451b230-1660-4838-a363-458298368c0d,
abstract = {{<p>Dual n-back WM training has been shown to produce broad transfer effects to different untrained cognitive functions. The task is demanding to the cognitive system because it includes a bi-modal (auditory and visual) dual-task component. A previous WM training study showed increased white matter integrity in the parietal lobe as well as the anterior part of the corpus callosum after visual n-back training. We investigated dual n-back training-related changes in white matter pathways. We anticipated dual n-back training to increase white matter integrity in pathways that connect brain regions related to WM processes. Additionally, we hypothesized that dual n-back training would produce more brain-wide white matter changes than single n-back training because of the involvement of two modalities and the additional dual-task coordination component of the task. The dual n-back training group showed increased white matter integrity (reflected as increased fractional anisotropy, FA) after training. The effects were mostly left lateralized as compared with changes from pretest to posttest in the passive and active control groups. Additionally, significant effects were observed in the anterior part of the corpus callosum, when the training group was compared with the passive control group. There were no changes in pretest to posttest FA changes between the passive and active control groups. The results therefore show that dual n-back training produces increased integrity in white matter pathways connecting different brain regions. The results are discussed in reference to the bi-modal dual-task component of the training task.</p>}},
author = {{Salminen, Tiina and Mårtensson, Johan and Schubert, Torsten and Kühn, Simone}},
issn = {{1053-8119}},
keywords = {{Plasticity; White matter; Working memory training}},
language = {{eng}},
month = {{06}},
pages = {{244--250}},
publisher = {{Elsevier}},
series = {{NeuroImage}},
title = {{Increased integrity of white matter pathways after dual n-back training}},
url = {{http://dx.doi.org/10.1016/j.neuroimage.2016.03.028}},
doi = {{10.1016/j.neuroimage.2016.03.028}},
volume = {{133}},
year = {{2016}},
}