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Innate and adaptive immunity in immune thrombocytopenia

Lazarus, Alan H; Semple, John W LU and Cines, Douglas B (2013) In Seminars in Hematology 50 (Suppl 1). p.68-70
Abstract

Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by both accelerated clearance of autoantibody-sensitized platelets and suboptimal platelet production. A number of studies have provided evidence of disturbed innate and adaptive immune responses in patients with ITP. This brief review will highlight some of the more recent work in this field and highlight other findings that provide a potential link between ITP, systemic lupus erythematosus (SLE), and autoimmune hemolytic anemia (AHA).

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author
publishing date
type
Contribution to journal
publication status
published
keywords
Adaptive Immunity, Animals, Humans, Immunity, Innate, Thrombocytopenia, Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Review
in
Seminars in Hematology
volume
50
issue
Suppl 1
pages
68 - 70
publisher
Elsevier
external identifiers
  • Scopus:84877654040
ISSN
0037-1963
DOI
10.1053/j.seminhematol.2013.03.012
language
English
LU publication?
no
id
5db58dc7-955f-4d6e-a3d8-ed09d739770c
date added to LUP
2016-09-23 12:02:27
date last changed
2016-10-23 04:45:53
@misc{5db58dc7-955f-4d6e-a3d8-ed09d739770c,
  abstract     = {<p>Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by both accelerated clearance of autoantibody-sensitized platelets and suboptimal platelet production. A number of studies have provided evidence of disturbed innate and adaptive immune responses in patients with ITP. This brief review will highlight some of the more recent work in this field and highlight other findings that provide a potential link between ITP, systemic lupus erythematosus (SLE), and autoimmune hemolytic anemia (AHA).</p>},
  author       = {Lazarus, Alan H and Semple, John W and Cines, Douglas B},
  issn         = {0037-1963},
  keyword      = {Adaptive Immunity,Animals,Humans,Immunity, Innate,Thrombocytopenia,Journal Article,Research Support, N.I.H., Extramural,Research Support, Non-U.S. Gov't,Review},
  language     = {eng},
  number       = {Suppl 1},
  pages        = {68--70},
  publisher    = {ARRAY(0x94b2990)},
  series       = {Seminars in Hematology},
  title        = {Innate and adaptive immunity in immune thrombocytopenia},
  url          = {http://dx.doi.org/10.1053/j.seminhematol.2013.03.012},
  volume       = {50 },
  year         = {2013},
}