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High 18F-FDG Uptake in synthetic aortic vascular grafts on PET/CT in symptomatic and asymptomatic patients

Wassélius, Johan LU ; Malmstedt, Jonas; Kalin, Bo; Larsson, Stig LU ; Sundin, Anders LU ; Hedin, Ulf and Jacobsson, Hans (2008) In Journal of Nuclear Medicine 49(10). p.5-1601
Abstract

UNLABELLED: Graft infection is a serious complication to vascular surgery. The aim of this study was to assess (18)F-FDG uptake in vascular grafts in patients with or without symptoms of graft infection.

METHODS: In all 2,045 patients examined by PET/CT at our clinic, 16 patients with synthetic aortic grafts were identified and reevaluated for (18)F-FDG accumulation. Clinical and biochemical data were obtained from patient records.

RESULTS: High (18)F-FDG uptake was found in 10 of 12 grafts in the patients who underwent open surgery and in 1 of 4 grafts in patients who underwent endovascular aneurysm repair. On the basis of biochemical and clinical data, it was concluded that 1 of the 16 patients had a graft infection at the... (More)

UNLABELLED: Graft infection is a serious complication to vascular surgery. The aim of this study was to assess (18)F-FDG uptake in vascular grafts in patients with or without symptoms of graft infection.

METHODS: In all 2,045 patients examined by PET/CT at our clinic, 16 patients with synthetic aortic grafts were identified and reevaluated for (18)F-FDG accumulation. Clinical and biochemical data were obtained from patient records.

RESULTS: High (18)F-FDG uptake was found in 10 of 12 grafts in the patients who underwent open surgery and in 1 of 4 grafts in patients who underwent endovascular aneurysm repair. On the basis of biochemical and clinical data, it was concluded that 1 of the 16 patients had a graft infection at the time of investigation.

CONCLUSION: (18)F-FDG uptake in vascular grafts was found in the vast majority of patients without graft infection. The risk of a false-positive diagnosis of graft infection by (18)F-FDG PET/CT is evident.

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author
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Contribution to journal
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published
subject
keywords
Aged, Aged, 80 and over, Aneurysm, Aorta, Aortic Aneurysm, Abdominal, Blood Vessel Prosthesis, Diagnostic Imaging, Female, Fluorodeoxyglucose F18, Humans, Male, Middle Aged, Positron-Emission Tomography, Radiopharmaceuticals, Tomography, X-Ray Computed, Journal Article, Research Support, Non-U.S. Gov't
in
Journal of Nuclear Medicine
volume
49
issue
10
pages
5 pages
publisher
Society of Nuclear Medicine
external identifiers
  • Scopus:53749090533
ISSN
0161-5505
DOI
10.2967/jnumed.108.053462
language
English
LU publication?
no
id
71008a2e-f8ea-463b-bfdf-af469fdbd7ad
date added to LUP
2016-10-14 09:58:01
date last changed
2016-10-17 10:41:34
@misc{71008a2e-f8ea-463b-bfdf-af469fdbd7ad,
  abstract     = {<p>UNLABELLED: Graft infection is a serious complication to vascular surgery. The aim of this study was to assess (18)F-FDG uptake in vascular grafts in patients with or without symptoms of graft infection.</p><p>METHODS: In all 2,045 patients examined by PET/CT at our clinic, 16 patients with synthetic aortic grafts were identified and reevaluated for (18)F-FDG accumulation. Clinical and biochemical data were obtained from patient records.</p><p>RESULTS: High (18)F-FDG uptake was found in 10 of 12 grafts in the patients who underwent open surgery and in 1 of 4 grafts in patients who underwent endovascular aneurysm repair. On the basis of biochemical and clinical data, it was concluded that 1 of the 16 patients had a graft infection at the time of investigation.</p><p>CONCLUSION: (18)F-FDG uptake in vascular grafts was found in the vast majority of patients without graft infection. The risk of a false-positive diagnosis of graft infection by (18)F-FDG PET/CT is evident.</p>},
  author       = {Wassélius, Johan and Malmstedt, Jonas and Kalin, Bo and Larsson, Stig and Sundin, Anders and Hedin, Ulf and Jacobsson, Hans},
  issn         = {0161-5505},
  keyword      = {Aged,Aged, 80 and over,Aneurysm,Aorta,Aortic Aneurysm, Abdominal,Blood Vessel Prosthesis,Diagnostic Imaging,Female,Fluorodeoxyglucose F18,Humans,Male,Middle Aged,Positron-Emission Tomography,Radiopharmaceuticals,Tomography, X-Ray Computed,Journal Article,Research Support, Non-U.S. Gov't},
  language     = {eng},
  number       = {10},
  pages        = {5--1601},
  publisher    = {ARRAY(0xc45b578)},
  series       = {Journal of Nuclear Medicine},
  title        = {High 18F-FDG Uptake in synthetic aortic vascular grafts on PET/CT in symptomatic and asymptomatic patients},
  url          = {http://dx.doi.org/10.2967/jnumed.108.053462},
  volume       = {49},
  year         = {2008},
}