High 18F-FDG Uptake in synthetic aortic vascular grafts on PET/CT in symptomatic and asymptomatic patients
(2008) In Journal of Nuclear Medicine 49(10). p.5-1601- Abstract
UNLABELLED: Graft infection is a serious complication to vascular surgery. The aim of this study was to assess (18)F-FDG uptake in vascular grafts in patients with or without symptoms of graft infection.
METHODS: In all 2,045 patients examined by PET/CT at our clinic, 16 patients with synthetic aortic grafts were identified and reevaluated for (18)F-FDG accumulation. Clinical and biochemical data were obtained from patient records.
RESULTS: High (18)F-FDG uptake was found in 10 of 12 grafts in the patients who underwent open surgery and in 1 of 4 grafts in patients who underwent endovascular aneurysm repair. On the basis of biochemical and clinical data, it was concluded that 1 of the 16 patients had a graft infection at the... (More)
UNLABELLED: Graft infection is a serious complication to vascular surgery. The aim of this study was to assess (18)F-FDG uptake in vascular grafts in patients with or without symptoms of graft infection.
METHODS: In all 2,045 patients examined by PET/CT at our clinic, 16 patients with synthetic aortic grafts were identified and reevaluated for (18)F-FDG accumulation. Clinical and biochemical data were obtained from patient records.
RESULTS: High (18)F-FDG uptake was found in 10 of 12 grafts in the patients who underwent open surgery and in 1 of 4 grafts in patients who underwent endovascular aneurysm repair. On the basis of biochemical and clinical data, it was concluded that 1 of the 16 patients had a graft infection at the time of investigation.
CONCLUSION: (18)F-FDG uptake in vascular grafts was found in the vast majority of patients without graft infection. The risk of a false-positive diagnosis of graft infection by (18)F-FDG PET/CT is evident.
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- author
- Wassélius, Johan LU ; Malmstedt, Jonas ; Kalin, Bo ; Larsson, Stig LU ; Sundin, Anders ; Hedin, Ulf and Jacobsson, Hans
- publishing date
- 2008-10
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Aged, Aged, 80 and over, Aneurysm, Aorta, Aortic Aneurysm, Abdominal, Blood Vessel Prosthesis, Diagnostic Imaging, Female, Fluorodeoxyglucose F18, Humans, Male, Middle Aged, Positron-Emission Tomography, Radiopharmaceuticals, Tomography, X-Ray Computed, Journal Article, Research Support, Non-U.S. Gov't
- in
- Journal of Nuclear Medicine
- volume
- 49
- issue
- 10
- pages
- 5 pages
- publisher
- Society of Nuclear Medicine
- external identifiers
-
- scopus:53749090533
- pmid:18794261
- ISSN
- 0161-5505
- DOI
- 10.2967/jnumed.108.053462
- language
- English
- LU publication?
- no
- id
- 71008a2e-f8ea-463b-bfdf-af469fdbd7ad
- date added to LUP
- 2016-10-14 09:58:01
- date last changed
- 2024-03-07 13:57:16
@article{71008a2e-f8ea-463b-bfdf-af469fdbd7ad, abstract = {{<p>UNLABELLED: Graft infection is a serious complication to vascular surgery. The aim of this study was to assess (18)F-FDG uptake in vascular grafts in patients with or without symptoms of graft infection.</p><p>METHODS: In all 2,045 patients examined by PET/CT at our clinic, 16 patients with synthetic aortic grafts were identified and reevaluated for (18)F-FDG accumulation. Clinical and biochemical data were obtained from patient records.</p><p>RESULTS: High (18)F-FDG uptake was found in 10 of 12 grafts in the patients who underwent open surgery and in 1 of 4 grafts in patients who underwent endovascular aneurysm repair. On the basis of biochemical and clinical data, it was concluded that 1 of the 16 patients had a graft infection at the time of investigation.</p><p>CONCLUSION: (18)F-FDG uptake in vascular grafts was found in the vast majority of patients without graft infection. The risk of a false-positive diagnosis of graft infection by (18)F-FDG PET/CT is evident.</p>}}, author = {{Wassélius, Johan and Malmstedt, Jonas and Kalin, Bo and Larsson, Stig and Sundin, Anders and Hedin, Ulf and Jacobsson, Hans}}, issn = {{0161-5505}}, keywords = {{Aged; Aged, 80 and over; Aneurysm; Aorta; Aortic Aneurysm, Abdominal; Blood Vessel Prosthesis; Diagnostic Imaging; Female; Fluorodeoxyglucose F18; Humans; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Tomography, X-Ray Computed; Journal Article; Research Support, Non-U.S. Gov't}}, language = {{eng}}, number = {{10}}, pages = {{5--1601}}, publisher = {{Society of Nuclear Medicine}}, series = {{Journal of Nuclear Medicine}}, title = {{High 18F-FDG Uptake in synthetic aortic vascular grafts on PET/CT in symptomatic and asymptomatic patients}}, url = {{http://dx.doi.org/10.2967/jnumed.108.053462}}, doi = {{10.2967/jnumed.108.053462}}, volume = {{49}}, year = {{2008}}, }