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Activity Quantification from Planar Images

Sjögreen Gleisner, Katarina LU (2022) In Series in Medical Physics and Biomedical Engineering 1.
Abstract
Planar imaging was for a long time the most-used technique for image-based activity quantification. Owing to its simplicity and speed, the possibility to acquire dynamic image sequences, and to generate whole-body images at a reasonable acquisition time, it is still frequently used in nuclear-medicine imaging. Today, planar imaging is most commonly used for diagnostic examinations with qualitative or semi-quantitative evaluation but is also performed for patients receiving radionuclide therapy. Activity quantification may then be applied to estimate the absorbed doses delivered to organs and tumours. It is well recognized that planar images suffer from the superposition of counts from activity located at different depths in the patient and... (More)
Planar imaging was for a long time the most-used technique for image-based activity quantification. Owing to its simplicity and speed, the possibility to acquire dynamic image sequences, and to generate whole-body images at a reasonable acquisition time, it is still frequently used in nuclear-medicine imaging. Today, planar imaging is most commonly used for diagnostic examinations with qualitative or semi-quantitative evaluation but is also performed for patients receiving radionuclide therapy. Activity quantification may then be applied to estimate the absorbed doses delivered to organs and tumours. It is well recognized that planar images suffer from the superposition of counts from activity located at different depths in the patient and that generally quantitative SPECT is superior for activity quantification. However, the techniques for planar-based activity quantification preceded and, in parts, formed the basis for the subsequent development of quantification methods from tomographic SPECT images, and these techniques still carry value in terms of understanding the process with which planar image projections are formed. Notably, also when acquisition is made in SPECT mode, the raw image data consist of a set of planar projections. Moreover, planar-based activity quantification is still used, for example, to estimate the total-body absorbed dose, and in combination with SPECT-based activity quantification in so-called hybrid planar/SPECT methods. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
host publication
Handbook of Nuclear Medicine and Molecular Imaging for Physicists : Instrumentation and Imaging Procedures - Instrumentation and Imaging Procedures
series title
Series in Medical Physics and Biomedical Engineering
editor
Ljungberg, Michael
volume
1
edition
1
pages
15 pages
publisher
CRC Press
ISBN
9780429489556
9781138593268
language
English
LU publication?
yes
id
0543e955-0307-45d4-a6d6-6af0e3f83e42
alternative location
https://www.taylorfrancis.com/chapters/edit/10.1201/9780429489556-25/activity-quantification-planar-images-katarina-sj%C3%B6green-gleisner?context=ubx&refId=6c24e4da-4d8a-480e-acb9-87ff816ada3e
date added to LUP
2023-05-26 11:02:46
date last changed
2023-05-26 11:02:46
@inbook{0543e955-0307-45d4-a6d6-6af0e3f83e42,
  abstract     = {{Planar imaging was for a long time the most-used technique for image-based activity quantification. Owing to its simplicity and speed, the possibility to acquire dynamic image sequences, and to generate whole-body images at a reasonable acquisition time, it is still frequently used in nuclear-medicine imaging. Today, planar imaging is most commonly used for diagnostic examinations with qualitative or semi-quantitative evaluation but is also performed for patients receiving radionuclide therapy. Activity quantification may then be applied to estimate the absorbed doses delivered to organs and tumours. It is well recognized that planar images suffer from the superposition of counts from activity located at different depths in the patient and that generally quantitative SPECT is superior for activity quantification. However, the techniques for planar-based activity quantification preceded and, in parts, formed the basis for the subsequent development of quantification methods from tomographic SPECT images, and these techniques still carry value in terms of understanding the process with which planar image projections are formed. Notably, also when acquisition is made in SPECT mode, the raw image data consist of a set of planar projections. Moreover, planar-based activity quantification is still used, for example, to estimate the total-body absorbed dose, and in combination with SPECT-based activity quantification in so-called hybrid planar/SPECT methods.}},
  author       = {{Sjögreen Gleisner, Katarina}},
  booktitle    = {{Handbook of Nuclear Medicine and Molecular Imaging for Physicists : Instrumentation and Imaging Procedures}},
  editor       = {{Ljungberg, Michael}},
  isbn         = {{9780429489556}},
  language     = {{eng}},
  month        = {{04}},
  publisher    = {{CRC Press}},
  series       = {{Series in Medical Physics and Biomedical Engineering}},
  title        = {{Activity Quantification from Planar Images}},
  url          = {{https://www.taylorfrancis.com/chapters/edit/10.1201/9780429489556-25/activity-quantification-planar-images-katarina-sj%C3%B6green-gleisner?context=ubx&refId=6c24e4da-4d8a-480e-acb9-87ff816ada3e}},
  volume       = {{1}},
  year         = {{2022}},
}