Current challenges in lung transplantation
(2025) In Journal of Internal Medicine 297(4). p.355-365- Abstract
Lung transplantation remains the definitive treatment for end-stage lung disease, but several critical challenges persist. Key issues include the limited availability of donor organs, ongoing debates over optimal preservation methods, and the controversy surrounding the best intraoperative support systems. Additionally, the efficacy of bridging strategies to transplantation continues to be questioned. This review delves into these pressing topics. This includes a focus on donation after cardiac death as a potential solution to expand the donor pool and recent advancements in hypothermic preservation, including innovative portable devices, and the role of bridging strategies. By addressing these multifaceted challenges, this review... (More)
Lung transplantation remains the definitive treatment for end-stage lung disease, but several critical challenges persist. Key issues include the limited availability of donor organs, ongoing debates over optimal preservation methods, and the controversy surrounding the best intraoperative support systems. Additionally, the efficacy of bridging strategies to transplantation continues to be questioned. This review delves into these pressing topics. This includes a focus on donation after cardiac death as a potential solution to expand the donor pool and recent advancements in hypothermic preservation, including innovative portable devices, and the role of bridging strategies. By addressing these multifaceted challenges, this review highlights the importance of continued advancements in donor management, organ preservation, and perioperative care to ultimately improve outcomes for lung transplant recipients.
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- author
- Niroomand, Anna LU and Lindstedt, Sandra LU
- organization
- publishing date
- 2025-04
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- donor management, lung transplantation, perioperative care
- in
- Journal of Internal Medicine
- volume
- 297
- issue
- 4
- pages
- 11 pages
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:85219634015
- pmid:40040535
- ISSN
- 0954-6820
- DOI
- 10.1111/joim.20072
- language
- English
- LU publication?
- yes
- additional info
- Publisher Copyright: © 2025 The Association for the Publication of the Journal of Internal Medicine.
- id
- 0570aa92-9261-4950-bc76-35bfcf65e85e
- date added to LUP
- 2025-06-24 15:08:00
- date last changed
- 2025-07-08 17:23:31
@article{0570aa92-9261-4950-bc76-35bfcf65e85e,
abstract = {{<p>Lung transplantation remains the definitive treatment for end-stage lung disease, but several critical challenges persist. Key issues include the limited availability of donor organs, ongoing debates over optimal preservation methods, and the controversy surrounding the best intraoperative support systems. Additionally, the efficacy of bridging strategies to transplantation continues to be questioned. This review delves into these pressing topics. This includes a focus on donation after cardiac death as a potential solution to expand the donor pool and recent advancements in hypothermic preservation, including innovative portable devices, and the role of bridging strategies. By addressing these multifaceted challenges, this review highlights the importance of continued advancements in donor management, organ preservation, and perioperative care to ultimately improve outcomes for lung transplant recipients.</p>}},
author = {{Niroomand, Anna and Lindstedt, Sandra}},
issn = {{0954-6820}},
keywords = {{donor management; lung transplantation; perioperative care}},
language = {{eng}},
number = {{4}},
pages = {{355--365}},
publisher = {{Wiley-Blackwell}},
series = {{Journal of Internal Medicine}},
title = {{Current challenges in lung transplantation}},
url = {{http://dx.doi.org/10.1111/joim.20072}},
doi = {{10.1111/joim.20072}},
volume = {{297}},
year = {{2025}},
}