Paradoxical increase in nasal airway resistance after topical nasal decongestion - does it really exist? : A retro- and prospective study
Swoboda, S LU
; Thulesius, H L
LU
and Jessen, M
(2016)
In Clinical Otolaryngology
41(6).
p.689-693
- Abstract
OBJECTIVE: To explore the prevalence and reproducibility of paradoxically increased nasal airway resistance after decongestion of the nasal mucosa as well as to identify patient-related factors associated with it.
DESIGN: Retrospective analysis of all rhinomanometric measurements carried out at one ENT department in Sweden in the time between 1990 and 2010. In the baseline material, 207 of 4435 patients (4.7%) showed a paradoxically increased nasal airway resistance >20%. A follow-up rhinomanometry was performed in patients eligible for the study.
SETTING: Secondary care centre.
PARTICIPANTS: Patients with paradoxically increased nasal airway resistance >20% who returned a complete questionnaire and had not... (More)
OBJECTIVE: To explore the prevalence and reproducibility of paradoxically increased nasal airway resistance after decongestion of the nasal mucosa as well as to identify patient-related factors associated with it.
DESIGN: Retrospective analysis of all rhinomanometric measurements carried out at one ENT department in Sweden in the time between 1990 and 2010. In the baseline material, 207 of 4435 patients (4.7%) showed a paradoxically increased nasal airway resistance >20%. A follow-up rhinomanometry was performed in patients eligible for the study.
SETTING: Secondary care centre.
PARTICIPANTS: Patients with paradoxically increased nasal airway resistance >20% who returned a complete questionnaire and had not undergone any nasal- or sinus surgery. Thirty-six patients (33-72 years) were eligible for the study.
MAIN OUTCOME MEASURES: All patients answered a questionnaire and underwent rhinoscopy. Nasal airway resistance before and after decongestion with 0.1% xylometazoline hydrochloride was assessed by active anterior rhinomanometry.
RESULTS: Twelve of thirty-six patients (33%) showed a paradoxically increased nasal airway resistance in the follow-up rhinomanometry. No patient-related factors were identified.
CONCLUSION: The results indicate the existence and reproducibility of paradoxically increased nasal airway resistance.
(Less)
- author
- Swoboda, S
LU
; Thulesius, H L
LU
and Jessen, M
- publishing date
- 2016
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Administration, Topical, Adult, Aged, Airway Resistance/physiology, Female, Humans, Male, Middle Aged, Nasal Decongestants/therapeutic use, Nasal Mucosa/physiopathology, Nasal Obstruction/drug therapy, Prospective Studies, Retrospective Studies, Rhinomanometry, Sweden
- in
- Clinical Otolaryngology
- volume
- 41
- issue
- 6
- pages
- 689 - 693
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:84975736376
- pmid:27870310
- ISSN
- 1749-4486
- DOI
- 10.1111/coa.12592
- language
- English
- LU publication?
- no
- additional info
- © 2015 John Wiley & Sons Ltd.
- id
- 07e48eef-d617-4f34-9f42-80638bdb16c2
- date added to LUP
- 2020-09-17 10:17:08
- date last changed
- 2024-03-05 11:07:50
@article{07e48eef-d617-4f34-9f42-80638bdb16c2,
abstract = {{<p>OBJECTIVE: To explore the prevalence and reproducibility of paradoxically increased nasal airway resistance after decongestion of the nasal mucosa as well as to identify patient-related factors associated with it.</p><p>DESIGN: Retrospective analysis of all rhinomanometric measurements carried out at one ENT department in Sweden in the time between 1990 and 2010. In the baseline material, 207 of 4435 patients (4.7%) showed a paradoxically increased nasal airway resistance >20%. A follow-up rhinomanometry was performed in patients eligible for the study.</p><p>SETTING: Secondary care centre.</p><p>PARTICIPANTS: Patients with paradoxically increased nasal airway resistance >20% who returned a complete questionnaire and had not undergone any nasal- or sinus surgery. Thirty-six patients (33-72 years) were eligible for the study.</p><p>MAIN OUTCOME MEASURES: All patients answered a questionnaire and underwent rhinoscopy. Nasal airway resistance before and after decongestion with 0.1% xylometazoline hydrochloride was assessed by active anterior rhinomanometry.</p><p>RESULTS: Twelve of thirty-six patients (33%) showed a paradoxically increased nasal airway resistance in the follow-up rhinomanometry. No patient-related factors were identified.</p><p>CONCLUSION: The results indicate the existence and reproducibility of paradoxically increased nasal airway resistance.</p>}},
author = {{Swoboda, S and Thulesius, H L and Jessen, M}},
issn = {{1749-4486}},
keywords = {{Administration, Topical; Adult; Aged; Airway Resistance/physiology; Female; Humans; Male; Middle Aged; Nasal Decongestants/therapeutic use; Nasal Mucosa/physiopathology; Nasal Obstruction/drug therapy; Prospective Studies; Retrospective Studies; Rhinomanometry; Sweden}},
language = {{eng}},
number = {{6}},
pages = {{689--693}},
publisher = {{Wiley-Blackwell}},
series = {{Clinical Otolaryngology}},
title = {{Paradoxical increase in nasal airway resistance after topical nasal decongestion - does it really exist? : A retro- and prospective study}},
url = {{http://dx.doi.org/10.1111/coa.12592}},
doi = {{10.1111/coa.12592}},
volume = {{41}},
year = {{2016}},
}