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Method for separation and purification of 13-dehydroxybaccatin III and 10-deacetylpaclitaxel from taxans-containing materials

Pyo, Sang-Hyun LU orcid ; Cho, Jin-Suk ; Kim, Moon‐Suk ; Song, Bong-Kyu and Choi, Ho-Joon (2007) US7880022B2
Abstract
This invention is directed to a method for efficiently separating and purifying 13-dehydroxybaccatin III and 10-deacetylpaclitaxel with a high purity of 90% or higher purity, preferably 99.5% or higher purity, from taxane-containing materials such as Taxus species, and the thusly obtained highly pure 13-dehydroxybaccatin III and 10-deacetylpaclitaxel can be used as semi-synthetic precursors of paclitaxel and/or docetaxel that are anticancer agents.
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inventor
LU orcid ; Cho, Jin-Suk ; Kim, Moon‐Suk ; Song, Bong-Kyu and Choi, Ho-Joon
publishing date
type
Patent
publication status
published
subject
publisher
United States Patent and Trademark Office
patent number
US7880022B2
language
English
LU publication?
no
id
0b29eaac-15fc-4aa1-b52b-5a05edb416f2
date added to LUP
2025-09-16 16:40:08
date last changed
2025-09-22 16:47:51
@misc{0b29eaac-15fc-4aa1-b52b-5a05edb416f2,
  abstract     = {{This invention is directed to a method for efficiently separating and purifying 13-dehydroxybaccatin III and 10-deacetylpaclitaxel with a high purity of 90% or higher purity, preferably 99.5% or higher purity, from taxane-containing materials such as Taxus species, and the thusly obtained highly pure 13-dehydroxybaccatin III and 10-deacetylpaclitaxel can be used as semi-synthetic precursors of paclitaxel and/or docetaxel that are anticancer agents.}},
  author       = {{Pyo, Sang-Hyun and Cho, Jin-Suk and Kim, Moon‐Suk and Song, Bong-Kyu and Choi, Ho-Joon}},
  language     = {{eng}},
  month        = {{05}},
  note         = {{Patent, Patent Number: US7880022B2}},
  publisher    = {{United States Patent and Trademark Office}},
  title        = {{Method for separation and purification of 13-dehydroxybaccatin III and 10-deacetylpaclitaxel from taxans-containing materials}},
  year         = {{2007}},
}