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Lipoteichoic acid is the major cell wall component responsible for surface hydrophobicity of group A streptococci

Miörner, Håkan LU ; Johansson, Göte and Kronvall, Göran (1983) In Infection and Immunity 39(1). p.336-343
Abstract
The contribution of lipoteichoic acid (LTA) to the hydrophobic surface properties of group A streptococci was investigated in aqueous dextran-polyethylene glycol two-phase systems. Enzymatic digestions were performed to characterize the hydrophobic surface structure. The results obtained indicated that LTA is a major factor responsible for the hydrophobic character of the cell surface of group A streptococci. This was further supported by the similarity of partition in polymer two-phase systems between whole group A streptococci and tritiated LTA extracted from a group A streptococcal strain. Surface LTA was also determined on intact organisms by a new method measuring the adsorption of antibodies to LTA to the bacterial surface. A... (More)
The contribution of lipoteichoic acid (LTA) to the hydrophobic surface properties of group A streptococci was investigated in aqueous dextran-polyethylene glycol two-phase systems. Enzymatic digestions were performed to characterize the hydrophobic surface structure. The results obtained indicated that LTA is a major factor responsible for the hydrophobic character of the cell surface of group A streptococci. This was further supported by the similarity of partition in polymer two-phase systems between whole group A streptococci and tritiated LTA extracted from a group A streptococcal strain. Surface LTA was also determined on intact organisms by a new method measuring the adsorption of antibodies to LTA to the bacterial surface. A correlation was found between the content of surface LTA and the hydrophobicity of the group A streptococci. We conclude that surface-associated LTA is the major factor determining surface hydrophobicity of group A streptococci. (Less)
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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Infection and Immunity
volume
39
issue
1
pages
336 - 343
publisher
American Society for Microbiology
external identifiers
  • pmid:6337099
  • scopus:0020695696
ISSN
1098-5522
language
English
LU publication?
yes
id
503d3c14-1d01-44f9-8be7-4f0e5a3f993f (old id 1103072)
alternative location
http://iai.asm.org/cgi/reprint/39/1/336
http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=347944&blobtype=pdf
date added to LUP
2016-04-01 11:38:48
date last changed
2025-04-04 14:33:48
@article{503d3c14-1d01-44f9-8be7-4f0e5a3f993f,
  abstract     = {{The contribution of lipoteichoic acid (LTA) to the hydrophobic surface properties of group A streptococci was investigated in aqueous dextran-polyethylene glycol two-phase systems. Enzymatic digestions were performed to characterize the hydrophobic surface structure. The results obtained indicated that LTA is a major factor responsible for the hydrophobic character of the cell surface of group A streptococci. This was further supported by the similarity of partition in polymer two-phase systems between whole group A streptococci and tritiated LTA extracted from a group A streptococcal strain. Surface LTA was also determined on intact organisms by a new method measuring the adsorption of antibodies to LTA to the bacterial surface. A correlation was found between the content of surface LTA and the hydrophobicity of the group A streptococci. We conclude that surface-associated LTA is the major factor determining surface hydrophobicity of group A streptococci.}},
  author       = {{Miörner, Håkan and Johansson, Göte and Kronvall, Göran}},
  issn         = {{1098-5522}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{336--343}},
  publisher    = {{American Society for Microbiology}},
  series       = {{Infection and Immunity}},
  title        = {{Lipoteichoic acid is the major cell wall component responsible for surface hydrophobicity of group A streptococci}},
  url          = {{http://iai.asm.org/cgi/reprint/39/1/336}},
  volume       = {{39}},
  year         = {{1983}},
}