Hyperplasia and hypertrophia in the denervated and distended rat urinary bladder
(1984) In Acta Physiologica Scandinavica 122(1). p.45-48- Abstract
- The parasympathetically denervated and distended rat urinary bladder was found to have increased fourfold in weight when examined 3 weeks postoperatively. Both in muscularis and mucosa of such a bladder the synthesis of proteins, RNA and DNA was increased severalfold. An increase in the polyamines putrescine, spermidine and spermine was also found; these polyamines are usually linked to protein synthesis. The results suggest that the cells of the two layers increase both in size and number. Hyperplasia was, in a previous study, suggested as a possible explanation for a right-ward shift of the active length-tension curve of muscle strips in the denervated rat urinary bladder.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1103269
- author
- Ekström, J ; Henningsson, Anne-Charlotte LU ; Henningsson, S and Malmberg, Lars LU
- organization
- publishing date
- 1984
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Acta Physiologica Scandinavica
- volume
- 122
- issue
- 1
- pages
- 45 - 48
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:6209921
- scopus:0021131448
- ISSN
- 0001-6772
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Department of Urology, Lund (013077000), Pediatrics/Urology/Gynecology/Endocrinology (013240400)
- id
- 4bed0513-672b-430a-853d-2030bd07a8dd (old id 1103269)
- date added to LUP
- 2016-04-01 16:17:32
- date last changed
- 2021-08-29 04:35:51
@article{4bed0513-672b-430a-853d-2030bd07a8dd, abstract = {{The parasympathetically denervated and distended rat urinary bladder was found to have increased fourfold in weight when examined 3 weeks postoperatively. Both in muscularis and mucosa of such a bladder the synthesis of proteins, RNA and DNA was increased severalfold. An increase in the polyamines putrescine, spermidine and spermine was also found; these polyamines are usually linked to protein synthesis. The results suggest that the cells of the two layers increase both in size and number. Hyperplasia was, in a previous study, suggested as a possible explanation for a right-ward shift of the active length-tension curve of muscle strips in the denervated rat urinary bladder.}}, author = {{Ekström, J and Henningsson, Anne-Charlotte and Henningsson, S and Malmberg, Lars}}, issn = {{0001-6772}}, language = {{eng}}, number = {{1}}, pages = {{45--48}}, publisher = {{Wiley-Blackwell}}, series = {{Acta Physiologica Scandinavica}}, title = {{Hyperplasia and hypertrophia in the denervated and distended rat urinary bladder}}, volume = {{122}}, year = {{1984}}, }