Disuse as cause of supersensitivity in the rat urinary bladder
(1986) In Acta Physiologica Scandinavica 126(3). p.429-432- Abstract
- Ureterostomia in situ was performed to reduce the nervous reflex activation of the bladders without concomitant hypertrophy. In muscle strips of these disused and non-hypertrophied bladders, supersensitivity to methacholine was demonstrated, which did not increase between 1 and 3 weeks. The supersensitivity did not increase further by combining urinary diversion with section of the preganglionic bladder nerves (decentralization). From the present results it may be concluded that in decentralized and hypertrophied bladders not only hypertrophy per se, previously studied (Ekstrom et al. 1985), but also loss of nerve impulse traffic (cf. urinary diversion) contribute to the development of supersensitivity.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1103620
- author
- Ekström, J and Malmberg, Lars LU
- organization
- publishing date
- 1986
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Acta Physiologica Scandinavica
- volume
- 126
- issue
- 3
- pages
- 429 - 432
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:3515849
- scopus:0022517968
- ISSN
- 0001-6772
- language
- English
- LU publication?
- yes
- id
- b679fa44-6f20-4f90-8913-03e8b1ed88ca (old id 1103620)
- date added to LUP
- 2016-04-01 15:43:49
- date last changed
- 2021-08-29 04:24:42
@article{b679fa44-6f20-4f90-8913-03e8b1ed88ca,
abstract = {{Ureterostomia in situ was performed to reduce the nervous reflex activation of the bladders without concomitant hypertrophy. In muscle strips of these disused and non-hypertrophied bladders, supersensitivity to methacholine was demonstrated, which did not increase between 1 and 3 weeks. The supersensitivity did not increase further by combining urinary diversion with section of the preganglionic bladder nerves (decentralization). From the present results it may be concluded that in decentralized and hypertrophied bladders not only hypertrophy per se, previously studied (Ekstrom et al. 1985), but also loss of nerve impulse traffic (cf. urinary diversion) contribute to the development of supersensitivity.}},
author = {{Ekström, J and Malmberg, Lars}},
issn = {{0001-6772}},
language = {{eng}},
number = {{3}},
pages = {{429--432}},
publisher = {{Wiley-Blackwell}},
series = {{Acta Physiologica Scandinavica}},
title = {{Disuse as cause of supersensitivity in the rat urinary bladder}},
volume = {{126}},
year = {{1986}},
}