Radio-iodobenzylguanidine scintigraphy of neuroblastoma: conflicting results, when compared with standard investigations
(1989) In Medical and Pediatric Oncology 17(2). p.126-130- Abstract
- Seventy-one patients with neuroblastoma (NB) and 25 patients with other neoplastic or nonneoplastic diseases were studied with MIBG scintigraphy. Sensitivity and specificity at diagnosis were 94% and 88%, respectively. Of 52 patients with NB studied during follow-up, 14 had on one or several occasions conflicting results, when the findings at MIBG scintigraphy were compared to standard investigations (SI: CT scan, bone scan, x-ray, and ultrasound). The correlation of MIBG scintigraphy and SI to clinical outcome were in these 14 patients not significantly different. Adding VMA-excretion measurements did not significantly improve the predictive value of MIBG scintigraphy or SI. Patients with tumor-suspected lesions only at MIBG scintigraphy... (More)
- Seventy-one patients with neuroblastoma (NB) and 25 patients with other neoplastic or nonneoplastic diseases were studied with MIBG scintigraphy. Sensitivity and specificity at diagnosis were 94% and 88%, respectively. Of 52 patients with NB studied during follow-up, 14 had on one or several occasions conflicting results, when the findings at MIBG scintigraphy were compared to standard investigations (SI: CT scan, bone scan, x-ray, and ultrasound). The correlation of MIBG scintigraphy and SI to clinical outcome were in these 14 patients not significantly different. Adding VMA-excretion measurements did not significantly improve the predictive value of MIBG scintigraphy or SI. Patients with tumor-suspected lesions only at MIBG scintigraphy should be followed closely and the nature of the lesions should be explored through biopsy. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1104695
- author
- organization
- publishing date
- 1989
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- MIBG scintigraphy, sensitivity, specificity, predictive value
- in
- Medical and Pediatric Oncology
- volume
- 17
- issue
- 2
- pages
- 126 - 130
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- pmid:2649775
- scopus:0024526167
- ISSN
- 1096-911X
- DOI
- 10.1002/mpo.2950170210
- language
- English
- LU publication?
- yes
- id
- 20cb017b-294b-4052-8745-02ce0a9bf8e3 (old id 1104695)
- date added to LUP
- 2016-04-01 11:41:34
- date last changed
- 2021-09-26 03:10:17
@article{20cb017b-294b-4052-8745-02ce0a9bf8e3, abstract = {{Seventy-one patients with neuroblastoma (NB) and 25 patients with other neoplastic or nonneoplastic diseases were studied with MIBG scintigraphy. Sensitivity and specificity at diagnosis were 94% and 88%, respectively. Of 52 patients with NB studied during follow-up, 14 had on one or several occasions conflicting results, when the findings at MIBG scintigraphy were compared to standard investigations (SI: CT scan, bone scan, x-ray, and ultrasound). The correlation of MIBG scintigraphy and SI to clinical outcome were in these 14 patients not significantly different. Adding VMA-excretion measurements did not significantly improve the predictive value of MIBG scintigraphy or SI. Patients with tumor-suspected lesions only at MIBG scintigraphy should be followed closely and the nature of the lesions should be explored through biopsy.}}, author = {{Schmiegelow, Kjeld and Simes, Martti A and Agertoft, Lone and Berglund, Gunilla and Storm-Mathisen, Ingebjörn and Andreassen, Michael and Salmi, Toivo T and Nygard, Randi and Wiebe, Thomas and Kreuger, Anders and Hayder, Salah}}, issn = {{1096-911X}}, keywords = {{MIBG scintigraphy; sensitivity; specificity; predictive value}}, language = {{eng}}, number = {{2}}, pages = {{126--130}}, publisher = {{John Wiley & Sons Inc.}}, series = {{Medical and Pediatric Oncology}}, title = {{Radio-iodobenzylguanidine scintigraphy of neuroblastoma: conflicting results, when compared with standard investigations}}, url = {{http://dx.doi.org/10.1002/mpo.2950170210}}, doi = {{10.1002/mpo.2950170210}}, volume = {{17}}, year = {{1989}}, }