Protein kinase C modulation of the ethanol effect on serotonin2 receptor transduction in astrocytes
(1989) In Alcohol and Alcoholism 24(5). p.401-404- Abstract
- Acute ethanol exposure stimulated serotonin2 receptor signalling in cultured astrocytes. Pretreatment with the protein kinase C inhibitor H7 significantly increased the ethanol-induced potentiation of [3H]-inositol phosphates accumulation. The increase could be explained by an augmented activation of phospholipase C. The results indicate a role of PKC for the modulation of ethanol effects on cellular signalling.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1104759
- author
- Simonsson, Per LU ; Hansson, Elisabeth and Alling, Christer LU
- organization
- publishing date
- 1989
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Alcohol and Alcoholism
- volume
- 24
- issue
- 5
- pages
- 401 - 404
- publisher
- Oxford University Press
- external identifiers
-
- pmid:2554934
- scopus:0024829805
- ISSN
- 1464-3502
- language
- English
- LU publication?
- yes
- id
- ef190104-f624-493e-a3a3-3ac25cf41b4c (old id 1104759)
- alternative location
- http://alcalc.oxfordjournals.org/cgi/reprint/24/5/401
- date added to LUP
- 2016-04-01 12:29:31
- date last changed
- 2021-01-03 07:35:28
@article{ef190104-f624-493e-a3a3-3ac25cf41b4c, abstract = {{Acute ethanol exposure stimulated serotonin2 receptor signalling in cultured astrocytes. Pretreatment with the protein kinase C inhibitor H7 significantly increased the ethanol-induced potentiation of [3H]-inositol phosphates accumulation. The increase could be explained by an augmented activation of phospholipase C. The results indicate a role of PKC for the modulation of ethanol effects on cellular signalling.}}, author = {{Simonsson, Per and Hansson, Elisabeth and Alling, Christer}}, issn = {{1464-3502}}, language = {{eng}}, number = {{5}}, pages = {{401--404}}, publisher = {{Oxford University Press}}, series = {{Alcohol and Alcoholism}}, title = {{Protein kinase C modulation of the ethanol effect on serotonin2 receptor transduction in astrocytes}}, url = {{http://alcalc.oxfordjournals.org/cgi/reprint/24/5/401}}, volume = {{24}}, year = {{1989}}, }